(R)-chloroquine

Base Information Edit

Chemical Name:(R)-chloroquine
CAS No.:58175-87-4
Molecular Formula:C₁₈H₂₆ClN₃
Molecular Weight:319.878
Hs Code.:
UNII:WE58C2WV1T
DSSTox Substance ID:DTXSID401316905
Nikkaji Number:J4.151C
Wikidata:Q27104631
Metabolomics Workbench ID:52494
ChEMBL ID:CHEMBL252715
Mol file:58175-87-4.mol

Synonyms:(R)-chloroquine;(-)-Chloroquine;58175-87-4;(R)-(-)-Chloroquine;Chloroquine, (R)-;WE58C2WV1T;CHEBI:48811;N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE;(4R)-4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (4R)-;(R)-N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine;CLQ;1cet;(?)-Chloroquine;UNII-WE58C2WV1T;BIDD:GT0138;SCHEMBL134500;CHEMBL252715;DTXSID401316905;E80614;Q27104631;(-)-N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine;(4R)-N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine;(4R)-N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine;(R)-N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine;1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (-)-;1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (R)-

Suppliers and Price of (R)-chloroquine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (R)-chloroquine Edit

Chemical Property:

Vapor Pressure:1.15E-08mmHg at 25°C
Boiling Point:460.6°C at 760 mmHg
Flash Point:232.3°C
PSA：28.16000
Density:1.111g/cm³
LogP:4.88360
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:319.1815255
Heavy Atom Count:22
Complexity:309

Purity/Quality:: HPLC≥98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
Isomeric SMILES:CCN(CC)CCC[C@@H](C)NC1=C2C=CC(=CC2=NC=C1)Cl

Technology Process of (R)-chloroquine

There total 15 articles about (R)-chloroquine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

: 86-98-6,1138471-54-1
4,7-dichloroquinoline

: 67459-50-1
(R)-(-)-4-amino-1-(diethylamino)pentane

: 54-05-7,56598-66-4,58175-86-3,58175-87-4
(R)-(-)-chloroquine

Guidance literature:: With potassium phosphate; palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; In toluene; at 80 - 85 ℃; for 2h; Solvent; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield: 68.0%

: 54-05-7
Chloroquine

: 54-05-7,56598-66-4,58175-86-3,58175-87-4
(R)-(-)-chloroquine

Guidance literature:: Chloroquine; With (S)-Malic acid; In ethanol; ethyl acetate; at 0 - 5 ℃; for 0.5h;

With sodium ethanolate; In methanol; at 0 - 20 ℃; for 0.5h;