propan-2-ylsulfinylbenzene

Base Information

• Chemical Name: propan-2-ylsulfinylbenzene
• CAS No.: 4170-69-8
• Molecular Formula: C9H12OS
• Molecular Weight: 168.26
• Hs Code.: 2930909090
• Mol file: 4170-69-8.mol

Synonyms:Sulfoxide,isopropyl phenyl (6CI,7CI,8CI);Isopropyl benzenesulfenate;Isopropyl phenylsulfoxide;NSC 316452;Phenyl isopropyl sulfoxide;Propan-2-ylsulfinylbenzene;

Chemical Property of propan-2-ylsulfinylbenzene

Chemical Property:

• Vapor Pressure: 0.00373mmHg at 25°C
• Refractive Index: 1.571
• Boiling Point: 289.9 °C at 760 mmHg
• Flash Point: 129.1 °C
• PSA: 36.28000
• Density: 1.11 g/cm³
• LogP: 3.06830

Purity/Quality:

99% ^*data from raw suppliers

ISOPROPYLPHENYL SULFOXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of propan-2-ylsulfinylbenzene

There total 48 articles about propan-2-ylsulfinylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

isopropylthiobenzene (3019-20-3) → isopropyl phenyl sulfoxide (4170-69-8)

Guidance literature:

isopropylthiobenzene; With Preyssler catalyst; titanium(IV) oxide; In isopropyl alcohol; at 20 ℃; for 0.25h;

With dihydrogen peroxide; In water; isopropyl alcohol; for 1.25h;

DOI:10.1016/j.molcata.2010.03.011

Reference yield: 85.0%

3-(isopropylsulfinyl)propionic acid tert-butyl ester (911820-11-6) + iodobenzene (591-50-4) → (R)-(isopropylsulfinyl)benzene (4170-69-8,73610-09-0,80225-50-9,34044-66-1)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; (R)-N-((1R)-(adamantan-1-yl)(5-(diphenylphosphanyl)-9,9-dimethyl-9H-xanthen-4-yl)methyl)-2-methylpropane-2-sulfinamide; caesium carbonate; In 1,3,5-trimethyl-benzene; at 60 ℃; for 90h; enantioselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1021/jacs.8b00178

Reference yield: 82.0%

bromobenzene (108-86-1,52753-63-6) + 2-propyl 2-(trimethylsilyl)ethyl sulfoxide (143505-46-8) → isopropyl phenyl sulfoxide (4170-69-8)

Guidance literature:

With 9-(2-(dicyclohexylphosphino)phenyl)-9H-carbazole; cesium fluoride; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 80 ℃; for 24h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/jacs.5b08117

upstream raw materials:

isopropylthiobenzene

phenylmagnesium bromide

isopropyl 2-pyridyl sulfoxide

[(methylthio)methyl]-benzene

Downstream raw materials:

phenyl isopropyl sulfone

(R)-(isopropylsulfinyl)benzene

(S)-isopropyl phenyl sulfoxide

(-)-(S)-tert-butyl [(2-diphenylphosphanyl)phenyl] sulfoxide

Refernces

• 1、 Yuan, Chengyuan,Liu, Honghai,Gao, Xionghou. "Magnetically recoverable heterogeneous catalyst: Tungstate intercalated Mg-Al-layered double hydroxides-encapsulated Fe3O4 nanoparticles for highly efficient selective oxidation of sulfides with H 2O2". . p. 16 - 21. Retrieved 2014.
• 2、 Lee, Sunwoo,Park, Jin Kyu. "Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides". . p. 13790 - 13799. Retrieved 2021/10/12.
• 3、 Fernández-Pérez, Héctor,Grabulosa, Arnald,Lao, Joan R.,Vidal-Ferran, Anton. "Exploiting Substrate Diversity for Preparing Synthetically Valuable Sulfoxides via Asymmetric Hydrogenative Kinetic Resolution". supporting information. . Retrieved 2020/07/24.