Trimethyl{3-[(trimethylsilyl)oxy]propyl}silane

Base Information

• Chemical Name: Trimethyl{3-[(trimethylsilyl)oxy]propyl}silane
• CAS No.: 17887-32-0
• Molecular Formula: C₉H₂₄OSi₂
• Molecular Weight: 204.46
• DSSTox Substance ID: DTXSID40513422
• Wikidata: Q82373235
• Mol file: 17887-32-0.mol

Synonyms:3-trimethylsilylpropyloxytrimethylsilane;17887-32-0;Trimethyl{3-[(trimethylsilyl)oxy]propyl}silane;SCHEMBL15202613;DTXSID40513422

Chemical Property of Trimethyl{3-[(trimethylsilyl)oxy]propyl}silane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 204.13656845
• Heavy Atom Count: 12
• Complexity: 122

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CCCO[Si](C)(C)C

Technology Process of Trimethyl{3-[(trimethylsilyl)oxy]propyl}silane

There total 1 articles about Trimethyl{3-[(trimethylsilyl)oxy]propyl}silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

trimethylene oxide (503-30-0) + chloro-trimethyl-silane (75-77-4) → (3-chloropropoxy)trimethylsilane (18171-15-8) + 2,2,7,7-tetramethyl-3-oxa-2,7-disila-octane (17887-32-0)

Guidance literature:

With sodium; In decane; for 3h; Heating;

DOI:10.1021/jo00349a034

Reference yield:

2,2,7,7-tetramethyl-3-oxa-2,7-disila-octane (17887-32-0) → (E)-trimethyl(3-phenylallyl)silane (40595-34-4)

Guidance literature:

Multi-step reaction with 6 steps

1: conc. HCl / 0.5 h / Heating

2: 1) oxalyl chloride, DMSO; 2) Et₃N / CH₂Cl₂; 1) -60 deg C, 15 min

3: 50 percent / Hexamethyldisilazane / petroleum ether / 1) -20 deg C, 20 min; 2) room temp., 2.5 h

4: 76.4 percent / diethyl ether / -80 °C

5: 80 percent / diethyl ether / 1) -95 deg C, 2.5 h; 2) -60 deg C, 0.5 h

6: 100 percent / N,N'-carbonyldiimidazole / toluene / 3 h / Heating; or with methanseulfonyl chloride, Et₃N at room temp.

With hydrogenchloride; oxalyl dichloride; dimethyl sulfoxide; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; 1,1'-carbonyldiimidazole; In diethyl ether; toluene; Petroleum ether;

DOI:10.1016/S0040-4020(01)89757-X

Reference yield:

2,2,7,7-tetramethyl-3-oxa-2,7-disila-octane (17887-32-0) → trimethyl<3-(4-methylphenyl)-2-propenyl>silane (111133-19-8)

Guidance literature:

Multi-step reaction with 6 steps

1: conc. HCl / 0.5 h / Heating

2: 1) oxalyl chloride, DMSO; 2) Et₃N / CH₂Cl₂; 1) -60 deg C, 15 min

3: 50 percent / Hexamethyldisilazane / petroleum ether / 1) -20 deg C, 20 min; 2) room temp., 2.5 h

4: 76.4 percent / diethyl ether / -80 °C

5: 81 percent / diethyl ether / 1) -95 deg C, 2.5 h; 2) -60 deg C, 0.5 h

6: 90 percent / N,N'-carbonyldiimidazole / toluene / 3 h / Heating

With hydrogenchloride; oxalyl dichloride; dimethyl sulfoxide; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; 1,1'-carbonyldiimidazole; In diethyl ether; toluene; Petroleum ether;

DOI:10.1016/S0040-4020(01)89757-X

upstream raw materials:

trimethylene oxide

chloro-trimethyl-silane

Downstream raw materials:

3-trimethylsilyl-1-propanol

3-(trimethylsilyl)propanal

(E)-trimethyl(3-phenylallyl)silane

trimethyl<3-(4-methylphenyl)-2-propenyl>silane

Refernces