5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose

Base Information

• Chemical Name: 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose
• CAS No.: 80244-96-8
• Molecular Formula: C10H16 O6
• Molecular Weight: 232.2304
• Mol file: 80244-96-8.mol

Synonyms:Furo[2,3-d]-1,3-dioxole,a-D-xylofuranose deriv.; NSC329370

Chemical Property of 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose

Chemical Property:

• Vapor Pressure: 5.66E-06mmHg at 25°C
• Boiling Point: 340.5°Cat760mmHg
• Flash Point: 130.4°C
• Density: 1.228g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose

There total 10 articles about 5-O-acetyl-1,2-O-(1-methylethylidene)pentofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1,2-O-isopropylidene-α-D-xylose (20031-21-4) + acetyl chloride (75-36-5) → 5-O-acetyl-1,2-O-isopropylidene-α-D-xylofuranose (80244-96-8)

Guidance literature:

With 2,4,6-trimethyl-pyridine; In dichloromethane; at -78 ℃;

DOI:10.1021/jo00067a005

Reference yield: 82.0%

1,2-O-isopropylidene-3,5-O-methoxyethylidene-α-D-xylofuranose → 5-O-acetyl-1,2-O-isopropylidene-α-D-xylofuranose (80244-96-8)

Guidance literature:

With water; toluene-4-sulfonic acid; In chloroform; for 30h; Ambient temperature;

DOI:10.1055/s-1995-3955

Reference yield: 77.0%

acetic pivalic mixed anhydride (7137-32-8) + 1,2-O-isopropylidene-α-D-xylose (20031-21-4) → 5-O-acetyl-1,2-O-isopropylidene-α-D-xylofuranose (80244-96-8)

Guidance literature:

In dichloromethane;

DOI:10.1016/j.tetlet.2004.03.045

upstream raw materials:

acetic anhydride

1,2-O-isopropylidene-α-D-xylose

3,5,6-tri-O-acetyl-1,2-O-isopropylidene-α-D-xylofuranose

Acetic acid (3aR,5R,6S,6aR)-6-(3,4-dimethoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl ester

Downstream raw materials:

C₂₄H₃₄N₂O₈

C₂₂H₃₂N₂O₆

C₂₂H₃₀N₂O₅

1,2-isopropylidene-α-D-ribofuranose

Refernces

• 1、 -. "NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND USES RELATED THERETO". Page/Page column 201; 202; 203; 204; 205. . Retrieved 2015/03/28.
• 2、 -. "NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES". Page/Page column 130-131. . Retrieved 2009/10/22.