3-(2H-tetrazol-5-yl)pyridine

Base Information Edit

Chemical Name:3-(2H-tetrazol-5-yl)pyridine
CAS No.:3250-74-6
Molecular Formula:C6H5N5
Molecular Weight:147.139
Hs Code.:2933990090
European Community (EC) Number:426-810-8,664-229-3
UNII:ZC84PPS834
DSSTox Substance ID:DTXSID50186227
Nikkaji Number:J989.465I
Wikidata:Q27295302
ChEMBL ID:CHEMBL179365
Mol file:3250-74-6.mol

Synonyms:5-(3-pyridyl)tetrazole;5-(3-pyridyl)tetrazole, 5-(13)C-labeled;P 5722;pyridyl-3-tetrazole

Suppliers and Price of 3-(2H-tetrazol-5-yl)pyridine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2H-Tetrazol-5-yl)pyridine
2.5g
$ 240.00

Sigma-Aldrich
5-(3-Pyridyl)-1H-tetrazole 97%
1g
$ 46.40

Matrix Scientific
5-(3-Pyridyl)-1H-tetrazole 98%
5g
$ 225.00

Matrix Scientific
5-(3-Pyridyl)-1H-tetrazole 98%
1g
$ 50.00

Crysdot
3-(2H-Tetrazol-5-yl)pyridine 98%
5g
$ 297.00

CHESS?
MC020260:3-(2H-Tetrazol-5-yl)-pyridine 98
5 g
$ 348.00

Chemenu
5-(3-Pyridyl)-1H-tetrazole 98%
5g
$ 281.00

American Custom Chemicals Corporation
5-(3-PYRIDYL)-1H-TETRAZOLE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
5-(3-PYRIDYL)-1H-TETRAZOLE 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
5-(3-PYRIDYL)-1H-TETRAZOLE 95.00%
1G
$ 692.46

Total 30 raw suppliers

Chemical Property of 3-(2H-tetrazol-5-yl)pyridine Edit

Chemical Property:

Vapor Pressure:5.88E-06mmHg at 25°C
Melting Point:240 °C
Boiling Point:379.4 °C at 760mmHg
PKA:5.99±0.12(Predicted)
Flash Point:192.2 °C
PSA：67.35000
Density:1.39 g/cm³
LogP:0.26170
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Water Solubility.:Soluble in water (slightly).
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:147.05449518
Heavy Atom Count:11
Complexity:128

Purity/Quality:

99.9% ^*data from raw suppliers

3-(2H-Tetrazol-5-yl)pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 20/21/22-36/37/38-22
Safety Statements: 26-36/37/39-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)C2=NNN=N2
Uses 5-(3-Pyridyl)-1H-tetrazole is used as a pharmaceutical intermediate. The Pyridine,3-(2H-tetrazol-5-yl)- acts as reactant with 1-(4-bromo-phenyl)-3-piperidino-propan-1-one, hydrochloride, and obtain the 1-(4-bromo-phenyl)-3-(5-pyridin-3-yl-tetrazol-2-yl)-propan-1-one. This reaction needs the solvent of dimethylformamide. The yield is 31%. In addition, this reaction should be taken for 8 hours at the temperature of 150°C.

Technology Process of 3-(2H-tetrazol-5-yl)pyridine

There total 10 articles about 3-(2H-tetrazol-5-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 100-54-9,121697-66-3,1232169-17-3,68271-95-4
pyridine-3-carbonitrile

: 3250-74-6,208264-85-1
3-(1H-tetrazol-5-yl)pyridine

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; for 24h; Reflux;
DOI:10.1002/jhet.382

Reference yield: 89.0%

: 1193-92-6
3-pyridinealdoxime

: 3250-74-6,208264-85-1
3-(1H-tetrazol-5-yl)pyridine

Guidance literature:: With indium(III) chloride; sodium azide; In N,N-dimethyl-formamide; at 120 ℃; for 14h;
DOI:10.1055/s-0035-1561559

Reference yield: 84.0%

: 500-22-1
3-pyridinecarboxaldehyde

: 3250-74-6,208264-85-1
3-(1H-tetrazol-5-yl)pyridine

Guidance literature:: With bismuth(lll) trifluoromethanesulfonate; sodium azide; acetylhydroxamic acid; In N,N-dimethyl-formamide; at 120 ℃; for 15h;
DOI:10.1055/s-0032-1318108