10-hydroxytetradecanoic acid

Base Information

• Chemical Name: 10-hydroxytetradecanoic acid
• CAS No.: 16899-08-4
• Molecular Formula: C14H28 O3
• Molecular Weight: 244.3703
• Mol file: 16899-08-4.mol

Synonyms:10-Hydroxymyristicacid; 10-Hydroxytetradecanoic acid

Chemical Property of 10-hydroxytetradecanoic acid

Chemical Property:

• Vapor Pressure: 2.14E-07mmHg at 25°C
• Melting Point: 56-57 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• Boiling Point: 381.7°Cat760mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 198.8°C
• PSA: 57.53000
• Density: 0.969g/cm³
• LogP: 3.74290

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 10-hydroxytetradecanoic acid

There total 12 articles about 10-hydroxytetradecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

myristoleic acid (544-64-9) → 10-hydroxytetradecanoic acid (16899-08-4)

Guidance literature:

With recombinant Chryseobacterium gleum oleate hydratase; In aq. phosphate buffer; at 25 ℃; for 21h; pH=6.5; Reagent/catalyst; Catalytic behavior;

DOI:10.1016/j.molcatb.2017.01.010

Reference yield: 48.0%

10-oxotetradecanoic acid (675-95-6) → 10-hydroxytetradecanoic acid (16899-08-4)

Guidance literature:

With hydrido(phosphonite)cobalt(I); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In 2-methyltetrahydrofuran; for 16h; chemoselective reaction; Sealed tube; Irradiation; Schlenk technique;

DOI:10.1002/anie.202114482

Reference yield:

n-tetradecanoic acid (544-63-8) → 11-hydroxymyristic acid (2034-56-2) + 10-hydroxytetradecanoic acid (16899-08-4) + 13-Hydroxymyristic acid (17278-73-8) + 12-hydroxytetradecanoic acid (82177-86-4) + 9-hydroxytetradecanoic acid (103273-05-8)

Guidance literature:

With glucose-6-phosphate dehydrogenase; D-glucose 6-phosphate; Sorangium cellulosum So ce56 cytochrome P₁₀₉D₁; Sorangium cellulosum So ce56 His-tagged ferredoxin reductase; NADP; magnesium chloride; for 0.5h; regioselective reaction; aq. buffer; Enzymatic reaction;

DOI:10.1016/j.chembiol.2010.10.010

upstream raw materials:

10-oxo-10-[2]thienyl-decanoic acid

1-methyl-4-nitrosobenzene

sodium myristoate

n-tetradecanoic acid

Downstream raw materials:

10-oxotetradecanoic acid

Refernces

• 1、 Cirino, Patrick C.,Arnold, Frances H.. "A self-sufficient peroxide-driven hydroxylation biocatalyst". . p. 3299 - 3301. Retrieved 2003.
• 2、 Joo, Young-Chul,Jeong, Ki-Woong,Yeom, Soo-Jin,Kim, Yeong-Su,Kim, Yangmee,Oh, Deok-Kun. "Biochemical characterization and FAD-binding analysis of oleate hydratase from Macrococcus caseolyticus". experimental part. p. 907 - 915. Retrieved 2012/05/19.