Benzenepropanamine, N-butyl-a-methyl-

Base Information

• Chemical Name: Benzenepropanamine, N-butyl-a-methyl-
• CAS No.: 68164-02-3
• Molecular Formula: C14H23N
• Molecular Weight: 205.343
• Mol file: 68164-02-3.mol

Synonyms:Benzenepropanamine, N-butyl-a-methyl-

Chemical Property of Benzenepropanamine, N-butyl-a-methyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenepropanamine, N-butyl-a-methyl-

There total 4 articles about Benzenepropanamine, N-butyl-a-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

4-Phenyl-2-butanone (2550-26-7) + N-butylamine (109-73-9,85404-21-3) + benzylamine borane → N-butyl-(1-methyl-3-phenyl)propylamine (68164-02-3) + N-benzyl-1-methyl-3-phenylpropylamine (68164-04-5)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1081/SCC-120002129

Reference yield:

Butyl-[1-methyl-3-phenyl-prop-(E)-ylidene]-amine; compound with acetic acid → N-butyl-(1-methyl-3-phenyl)propylamine (68164-02-3)

Guidance literature:

With magnesium; acetic acid; In methanol; Yield given; 1.) reflux, 2 h, 2.) reflux, 1 h;

DOI:10.1039/P19960000265

Reference yield:

methyl bromide (74-83-9) + N-β-phenylpropylidene-butylamine (90496-14-3) → N-butyl-(1-methyl-3-phenyl)propylamine (68164-02-3)

Guidance literature:

DOI:10.1016/S0040-4039(01)80106-4

upstream raw materials:

methyl bromide

N-β-phenylpropylidene-butylamine

4-Phenyl-2-butanone

N-butylamine

Downstream raw materials:

4-Phenyl-2-butanone

Refernces

• 1、 Micovic, Ivan V.,Ivanovic,Roglic, Goran M.,Kiricojevic, Vesna D.,Popovic, Jelena B.. "Preparation of secondary amines by reductive animation with metallic magnesium". . p. 265 - 269. Retrieved 2007/10/03.