4-HYDROXYPYRIDINE-1-OXIDE

Base Information

• Chemical Name: 4-HYDROXYPYRIDINE-1-OXIDE
• CAS No.: 6890-62-6
• Molecular Formula: C5H5NO2
• Molecular Weight: 111.1
• Hs Code.: 2933399090
• Mol file: 6890-62-6.mol

Synonyms:4-Hydroxypyridine1-oxide;4-Hydroxypyridine N-oxide;NSC 78419;

Chemical Property of 4-HYDROXYPYRIDINE-1-OXIDE

Chemical Property:

• Vapor Pressure: 0.0129mmHg at 25°C
• Refractive Index: 1.628
• Boiling Point: 387.694 °C at 760 mmHg
• Flash Point: 188.271 °C
• PSA: 45.69000
• Density: 1.241 g/cm³
• LogP: 0.82070

Purity/Quality:

99%, ^*data from raw suppliers

4-HYDROXYPYRIDIN-1-IUM-1-OLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXYPYRIDINE-1-OXIDE

There total 5 articles about 4-HYDROXYPYRIDINE-1-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-(N-pyridinium)pyridine-N-oxide chloride tetracyanoethylene complex (137858-02-7) → 4-hydroxypyridine N-oxide (6890-62-6)

Guidance literature:

With potassium hydroxide; at 40 ℃; for 4h;

DOI:10.1007/BF01169672

Reference yield:

4-nitraminopyridine N-oxide (1124-33-0) + acetic anhydride (108-24-7) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 4-hydroxypyridine N-oxide (6890-62-6)

Guidance literature:

DOI:10.1021/jo01133a010

Reference yield:

pyridine N-oxide (694-59-7) → 3-hydroxypyridine N-oxide (6602-28-4) + 4-hydroxypyridine N-oxide (6890-62-6) + 2-hydroxy-pyridine N-oxide (13161-30-3)

Guidance literature:

With water; hexachloroiridate(IV); dinitrogen monoxide; Rate constant; Irradiation;

DOI:10.1021/j100442a017

upstream raw materials:

4-nitraminopyridine N-oxide

acetic anhydride

N,N-dimethyl-aniline

pyridine N-oxide

Downstream raw materials:

pyridin-4-ol

Refernces

• 1、 Neta, P.,Steenken, S.,Janzen, Edward G.,Shetty, Raghav V.. "Pattern of Addition of Hydroxyl Radicals to the Spin Traps α-Pyridyl 1-Oxide N-tert-Butyl Nitrone". . p. 532 - 534. Retrieved 2007/10/02.