1,1'-Bipiperidine

Base Information

• Chemical Name: 1,1'-Bipiperidine
• CAS No.: 6130-94-5
• Molecular Formula: C10H20N2
• Molecular Weight: 168.282
• DSSTox Substance ID: DTXSID40902610
• Nikkaji Number: J1.630.004G
• Wikidata: Q27121621
• Metabolomics Workbench ID: 57289
• Mol file: 6130-94-5.mol

Synonyms:1,1'-Bipiperidine;6130-94-5;1-piperidin-1-ylpiperidine;bipiperidine;piperidino-piperidine;piperidylpiperidine;piperidinopiperidine;piperidinylpiperidine;[1,1']Bipiperidinyl;NoName_3145;SCHEMBL42220;CHEBI:49329;DTXSID40902610;AKOS015900295;Q27121621

Chemical Property of 1,1'-Bipiperidine

Chemical Property:

• Boiling Point: 247.2°Cat760mmHg
• Flash Point: 95.3°C
• PSA: 6.48000
• Density: 0.997g/cm³
• LogP: 1.74900
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 168.162648646
• Heavy Atom Count: 12
• Complexity: 108

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)N2CCCCC2

Technology Process of 1,1'-Bipiperidine

There total 4 articles about 1,1'-Bipiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

piperidine (110-89-4) → 1-(piperidin-1-yl)piperidine (6130-94-5) + N-Formylpiperidine (2591-86-8)

Guidance literature:

With sodium hydroxide; sodium persulfate; silver nitrate; In water; at 0 ℃; for 2.5h;

DOI:10.1007/BF00956799

Reference yield: 48.0%

piperidine (110-89-4) → 2,3,4,5-tetrahydropyridine (505-18-0) + 1-(piperidin-1-yl)piperidine (6130-94-5)

Guidance literature:

With sodium hydroxide; sodium persulfate; silver nitrate; In ammonium hydroxide; water; for 2.5h; Yields of byproduct given; below 10 deg C;

Reference yield:

piperidine (110-89-4) + lithium piperidide (4442-11-9) → 2,3,4,5-tetrahydropyridine (505-18-0) + 1-(piperidin-1-yl)piperidine (6130-94-5)

Guidance literature:

With oxygen; copper(l) chloride; In diethyl ether; at 35 ℃; Yield given. Yields of byproduct given; FeCl₃; CoCl₂; NiCl₂;

upstream raw materials:

piperidine

lithium piperidide

N,N'-bis(piperidino)diazene

Downstream raw materials:

5-amino-2-(4-piperidinopiperidin-1-yl)benzonitrile

1,2-Dipropyl-1,2-dimethylhydrazin

[1,1']Bipiperidinyl

dimethyl-piperidin-1-yl-amine

Refernces

• 1、 Troyanskii, E. I.,Ioffe, V. A.,Nikishin, G. I.. "OXIDATION OF AZACYCLOALKANES". . p. 2351 - 2359. Retrieved 2007/10/02.
• 2、 Ogawa, Keiichiro,Nomura, Yujiro,Takeuchi, Yoshito,Tomoda, Shuji. "Silver(I)-catalyzed Oxidation of Cyclic Secondary Amines with Peroxodisulphate". . p. 3031 - 3036. Retrieved 2007/10/02.