TRIFLUOROMETHYL METHYL ETHER

Base Information

• Chemical Name: TRIFLUOROMETHYL METHYL ETHER
• CAS No.: 421-14-7
• Molecular Formula: C2H3 F3 O
• Molecular Weight: 100.04
• Hs Code.: 2909199090
• Mol file: 421-14-7.mol

Synonyms:Ether,methyl trifluoromethyl (7CI,8CI); HFE 143a; HFE 143m; Methyl perfluoromethylether; Methyl trifluoromethyl ether; Trifluoromethoxymethane

Chemical Property of TRIFLUOROMETHYL METHYL ETHER

Chemical Property:

• Vapor Pressure: 17500mmHg at 25°C
• Melting Point: -149°C
• Refractive Index: 1.3488 (estimate)
• Boiling Point: -24°C
• Flash Point: °C
• PSA: 9.23000
• Density: 1.186g/cm³
• LogP: 1.15260

Purity/Quality:

98%min ^*data from raw suppliers

Trifluoromethyl methyl ether 99% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 11
• Safety Statements: 3/7-9-16-33

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRIFLUOROMETHYL METHYL ETHER

There total 10 articles about TRIFLUOROMETHYL METHYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.8%

Carbonyl fluoride (353-50-4) + carbonic acid dimethyl ester (616-38-6) → methyltrifluoromethyl ether (421-14-7)

Guidance literature:

Carbonyl fluoride; With cesium fluoride; In acetonitrile; at 20 ℃; for 24h; Autoclave;

carbonic acid dimethyl ester; With water; at 20 ℃; for 24h; Autoclave;

Reference yield: 80.0%

cesium trifluoromethoxide (2700-82-5) + dimethyl sulfate (77-78-1) → methyltrifluoromethyl ether (421-14-7)

Guidance literature:

at 19.9 ℃; for 96h;

DOI:10.1515/znb-1996-0127

Reference yield: 50.0%

trifluoromethyl hypochlorite (22082-78-6) + methyl iodide (74-88-4) → methyltrifluoromethyl ether (421-14-7)

Guidance literature:

at -70.1 ℃; for 1h;

DOI:10.1515/znb-1996-0127

upstream raw materials:

methanol

Carbonyl fluoride

trifluoronitrosomethane

Na salt of N-trifluoromethyl-N-nitroso-hydroxylamine

Downstream raw materials:

C₂₇H₃₃NO₅

Carbonyl fluoride

carbon dioxide

Trifluoromethyl formate

Refernces

• 1、 -. "Method for preparing fluorine-containing ether". Paragraph 0080-0081. . Retrieved 2019/07/29.
• 2、 Cheburkov, Yuri,Lillquist, Gerald J.. "Perfluoroalcohols". . p. 123 - 126. Retrieved 2007/10/03.