Boronic acid, (2,5-dimethyl-1,4-phenylene)bis-

Base Information

• Chemical Name: Boronic acid, (2,5-dimethyl-1,4-phenylene)bis-
• CAS No.: 90085-60-2
• Molecular Formula: C8H12B2O4
• Molecular Weight: 193.803
• Mol file: 90085-60-2.mol

Synonyms:

Chemical Property of Boronic acid, (2,5-dimethyl-1,4-phenylene)bis-

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Boronic acid, (2,5-dimethyl-1,4-phenylene)bis-

There total 5 articles about Boronic acid, (2,5-dimethyl-1,4-phenylene)bis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1,4-dimethyl-2,5-di(4’,4’,5’,5’-tetramethyl[1,3,2’]dioxaborolan-2’-yl)benzene (303006-89-5) → 2,5-dimethyl-1,4-benzenediboronic acid (90085-60-2)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 18h; Inert atmosphere;

DOI:10.1002/anie.202102982

Reference yield: 66.0%

Triisopropyl borate (5419-55-6) + 2,5-dibromo-p-xylene (1074-24-4) + water (7732-18-5) → 2,5-dimethyl-1,4-benzenediboronic acid (90085-60-2)

Guidance literature:

2,5-dibromo-p-xylene; With iodine; magnesium; In tetrahydrofuran; for 20h; Inert atmosphere; Reflux;

Triisopropyl borate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

water; With hydrogenchloride; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/anie.201906606

Reference yield:

2,5-dibromo-p-xylene (1074-24-4) → 2,5-dimethyl-1,4-benzenediboronic acid (90085-60-2)

Guidance literature:

With boric acid tributyl ester; magnesium; In tetrahydrofuran;

DOI:10.1021/jo01032a536

upstream raw materials:

2,5-dibromo-p-xylene

Triisopropyl borate

water

para-xylene

Downstream raw materials:

3-mer-HCA

6,6'-dimethyl-2,2'-(2,5-dimethyl-p-phenylene)-bis-[1,3,6,2]dioxazaborocane

Refernces

• 1、 Mutruc, Dragos,Goulet-Hanssens, Alexis,Fairman, Sam,Wahl, Sebastian,Zimathies, Annett,Knie, Christopher,Hecht, Stefan. "Modulating Guest Uptake in Core–Shell MOFs with Visible Light". supporting information. p. 12862 - 12867. Retrieved 2019/08/08.