Indan-5-carbaldehyde

Base Information

• Chemical Name: Indan-5-carbaldehyde
• CAS No.: 30084-91-4
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• Hs Code.: 2912299000
• European Community (EC) Number: 250-036-8
• UNII: V816D1X892
• DSSTox Substance ID: DTXSID70184169
• Nikkaji Number: J249.918E
• Wikidata: Q27291645
• Mol file: 30084-91-4.mol

Synonyms:Indan-5-carbaldehyde;30084-91-4;Indan-5-carboxaldehyde;2,3-dihydro-1H-indene-5-carbaldehyde;5-formylindan;5-indanecarboxaldehyde;indane-5-carboxaldehyde;5-Indancarboxaldehyde;indane-5-carbaldehyde;indan-5-carboxyaldehyde;1H-Indene-5-carboxaldehyde, 2,3-dihydro-;MFCD00086208;UNII-V816D1X892;EINECS 250-036-8;V816D1X892;2,3-dihydro-1H-indene-5-carboxaldehyde;5-formylindane;5-Indancarbaldehyde;Indan-5-carbaldehyd;SCHEMBL1525801;DTXSID70184169;5-indancarboxaldehyde, AldrichCPR;3,4-TRIMETHYLENEBENZALDEHYDE;AKOS000346317;CS-W007269;SB36463;AC-23004;AM803656;DS-13777;BB 0253398;FT-0658443;EN300-95762;A820189;J-017775;Q27291645;Z385369954

Chemical Property of Indan-5-carbaldehyde

Chemical Property:

• Vapor Pressure: 0.011mmHg at 25°C
• Melting Point: 255-257 °C
• Refractive Index: 1.61
• Boiling Point: 262.313 °C at 760 mmHg
• Flash Point: 139.744 °C
• PSA: 17.07000
• Density: 1.123 g/cm³
• LogP: 1.98780
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 146.073164938
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

98%, ^*data from raw suppliers

Indan-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Statements: 52

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C1)C=C(C=C2)C=O

Technology Process of Indan-5-carbaldehyde

There total 22 articles about Indan-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Dichloromethyl methyl ether (4885-02-3) + INDANE (496-11-7) → indan-5-carbaldehyde (30084-91-4)

Guidance literature:

With tin(IV) chloride; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/jm00075a027

Reference yield: 96.0%

(2,3-dihydro-1H-inden-5-yl)methanol (51632-06-5) → indan-5-carbaldehyde (30084-91-4)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1007/BF00809674

Reference yield: 84.0%

INDANE (496-11-7) + hexamethylenetetramine (100-97-0) → indan-5-carbaldehyde (30084-91-4)

Guidance literature:

With trifluoroacetic acid; at 100 ℃; for 5h;

upstream raw materials:

INDANE

5-chloromethylindane

Dichloromethyl methyl ether

carbon monoxide

Downstream raw materials:

3-(5-Indanyl)-prop-2-ensaeure

3t-(indanyl-⁽⁵⁾)-acrylic acid

indan-5-carboxylic acid

(2,3-dihydro-1H-inden-5-yl)methanol

Refernces

• 1、 Wightman,R.H. et al.. "-". . p. 2167 - 2170. Retrieved 1978.
• 2、 Konishi, Hideyuki,Kumon, Minoru,Yamaguchi, Miyuki,Manabe, Kei. "Palladium-catalyzed external-CO-free reductive carbonylation of aryl sulfonates". . . Retrieved 2020/10/29.
• 3、 -. "BI-CYCLO ALDEHYDE AS PERFUMING INGREDIENT". Page/Page column 8-9. . Retrieved 2015/01/16.