3,5-Dimethoxy-2-naphthoic acid

Base Information

• Chemical Name: 3,5-Dimethoxy-2-naphthoic acid
• CAS No.: 98410-68-5
• Molecular Formula: C₁₃H₁₂O₄
• Molecular Weight: 232.236
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID80361388
• Wikidata: Q82143709
• ChEMBL ID: CHEMBL1608067
• Mol file: 98410-68-5.mol

Synonyms:3,5-dimethoxy-2-naphthoic acid;98410-68-5;3,5-dimethoxynaphthalene-2-carboxylic acid;MLS000066539;SCHEMBL551105;3,5-dimethoxy-2-naphthoicacid;3,5-Dimethoxyisonaphthoic Acid;CHEMBL1608067;DTXSID80361388;HMS2481B15;MFCD05857770;STK663862;AKOS001740053;3,5-Dimethoxy-2-naphthoic acid, 97%;3 5-DIMETHOXY-2-NAPHTHOIC ACID;LS-07627;SMR000081647;3,5-dimethoxy-naphthalene-2-carboxylic acid;CS-0316777;SR-01000296066;SR-01000296066-1

Chemical Property of 3,5-Dimethoxy-2-naphthoic acid

Chemical Property:

• Vapor Pressure: 5.74E-07mmHg at 25°C
• Melting Point: 167-171oC(lit.)
• Boiling Point: 395.6oC at 760 mmHg
• Flash Point: 153.1oC
• PSA: 55.76000
• Density: 1.261g/cm3
• LogP: 2.55520
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 232.07355886
• Heavy Atom Count: 17
• Complexity: 279

Purity/Quality:

98% ^*data from raw suppliers

3,5-Dimethoxy-2-naphthoic acid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC2=CC(=C(C=C21)OC)C(=O)O

Technology Process of 3,5-Dimethoxy-2-naphthoic acid

There total 2 articles about 3,5-Dimethoxy-2-naphthoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dihydroxynaphthoic acid + dimethyl sulfate (77-78-1) → 3,5-dimethoxy-2-naphthoic acid (98410-68-5)

Guidance literature:

3,5-dihydroxynaphthoic acid; dimethyl sulfate; With potassium carbonate; In acetone; at 50 ℃; for 12h;

With potassium hydroxide; In methanol; water; at 65 ℃; for 3h;

Reference yield:

1,7-dimethoxynaphthalene (5309-18-2) → 3,5-dimethoxy-2-naphthoic acid (98410-68-5)

Guidance literature:

With n-butyllithium; diethyl ether; anschliessend mit festem CO₂ behandeln;

DOI:10.1021/ja01526a065

upstream raw materials:

1,7-dimethoxynaphthalene

dimethyl sulfate

Refernces

• 1、 -. "SULFONATE COMPOUND, PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY". Paragraph 0138. . Retrieved 2017/09/02.