1,7-DIMETHOXYNAPHTHALENE

Base Information

• Chemical Name: 1,7-DIMETHOXYNAPHTHALENE
• CAS No.: 5309-18-2
• Molecular Formula: C12H12O2
• Molecular Weight: 188.226
• Hs Code.: 2909309090
• Mol file: 5309-18-2.mol

Synonyms:1,7-Dimethoxynaphthalene;NSC 59835;

Chemical Property of 1,7-DIMETHOXYNAPHTHALENE

Chemical Property:

• Vapor Pressure: 0.00105mmHg at 25°C
• Refractive Index: n20/D 1.6160(lit.)
• Boiling Point: 311.2 °C at 760 mmHg
• Flash Point: 130.3 °C
• PSA: 18.46000
• Density: 1.097g/cm³
• LogP: 2.85700
• Storage Temp.: 2-8°C

Purity/Quality:

99.3% ^*data from raw suppliers

1,7-Dimethoxynaphthalene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 1,7-DIMETHOXYNAPHTHALENE

There total 14 articles about 1,7-DIMETHOXYNAPHTHALENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,7-Dihydroxynaphthalene (575-38-2) + dimethyl sulfate (77-78-1) → 1,7-dimethoxynaphthalene (5309-18-2)

Guidance literature:

With potassium hydroxide; In water; for 5h;

Reference yield: 84.0%

7-methoxynaphth-1-ol (67247-13-6) + dimethyl sulfate (77-78-1) → 1,7-dimethoxynaphthalene (5309-18-2)

Guidance literature:

With potassium carbonate; In acetone;

DOI:10.1016/0040-4020(95)00715-K

Reference yield: 74.0%

methanol (67-56-1) + 1,7-Dihydroxynaphthalene (575-38-2) → 1,7-dimethoxynaphthalene (5309-18-2) + 7-methoxynaphth-1-ol (67247-13-6)

Guidance literature:

With hydrogenchloride; for 168h; Ambient temperature;

DOI:10.1071/CH9930731

upstream raw materials:

4,6-Dimethoxy-naphthalin-carbonsaeure-(2)

1,7-Dihydroxynaphthalene

dimethyl sulfate

diazomethane

Downstream raw materials:

8-methoxy-2-tetralone

3,5-dimethoxy-2-naphthoic acid

Refernces

• 1、 Takeya, Tetsuya,Takahashi, Yosuke,Okamoto, Iwao,Tamura, Osamu. "Oxidative dimerization of 4-methoxynaphthylamines in the presence of semiconductors". experimental part. p. 1479 - 1488. Retrieved 2010/10/20.
• 2、 Kuo,Gillespie,Kulanthaivel,Lantz,Ma,Nelson,Threlkeld,Wheeler,Yi,Zmijewski. "Synthesis and biological activity of some known and putative duloxetine metabolites". . p. 3481 - 3486. Retrieved 2007/10/03.