67247-13-6 Usage
Description
7-Methoxy-1-naphthol, also known as A430000, is an organic compound with the chemical formula C11H10O2. It is a pale yellow solid and is primarily recognized for its role in the synthesis of Agomelatine, a pharmaceutical compound with potential applications in the treatment of various conditions.
Uses
Used in Pharmaceutical Industry:
7-Methoxy-1-naphthol is used as an intermediate in the synthesis of Agomelatine (A430000) for its potential therapeutic applications. Agomelatine is a melatonin receptor agonist and serotonin receptor antagonist, which has been studied for its effects on mood regulation and sleep-wake cycles, making it a candidate for the treatment of conditions such as major depressive disorder and insomnia.
Additionally, due to its chemical properties as a pale yellow solid, 7-Methoxy-1-naphthol may also find applications in other industries, such as in the production of dyes, pigments, or as a chemical intermediate for other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 67247-13-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,4 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67247-13:
(7*6)+(6*7)+(5*2)+(4*4)+(3*7)+(2*1)+(1*3)=136
136 % 10 = 6
So 67247-13-6 is a valid CAS Registry Number.
67247-13-6Relevant articles and documents
Read,G. et al.
, p. 2059 - 2068 (1969)
Enzymatic resolution of 5-hydroxy- and 8-hydroxy-2-tetralols using immobilized lipases
Bonomi, Paolo,Cairoli, Paola,Ubiali, Daniela,Morelli, Carlo F.,Filice, Marco,Nieto, Ines,Pregnolato, Massimo,Manitto, Paolo,Terreni, Marco,Speranza, Giovanna
scheme or table, p. 467 - 472 (2009/09/06)
(R)-2-Tetralol (R)-2a, (R)-5-hydroxy-2-tetralol (R)-2b and (R)-8-hydroxy-2-tetralol (R)-2c, which are key intermediates in the synthesis of pharmacologically active 2-aminotetralins 3, were prepared in moderate to very high enantiomeric excess (up to 99% ee) by enzymatic resolution of the corresponding racemic butyrates rac-1a, rac-1b and rac-1c, respectively, using lipases immobilized on octyl agarose. This methodology is an alternative to the microbial reduction of 2-tetralones.
Synthesis of a C8 oxygenated pyranonaphthoquinone: a useful precursor to dimeric pyranonaphthoquinones
Bachu, Prabhakar,Sperry, Jonathan,Brimble, Margaret A.
, p. 3343 - 3350 (2008/09/19)
The synthesis of a pyranonaphthoquinone bearing an oxygenated substituent at C8 is reported. The oxygen substituent at C8 provides a key functionality for use as a homocoupling precursor for the synthesis of a dimeric pyranonaphthoquinone.
