Saphris hydrochloride

Base Information

• Chemical Name: Saphris hydrochloride
• CAS No.: 1412458-61-7
• Molecular Formula: C₁₇H₁₆ClNO*ClH
• Molecular Weight: 322.234
• Mol file: 1412458-61-7.mol

Synonyms:CS-1053;

Chemical Property of Saphris hydrochloride

Chemical Property:

• PSA: 12.47000
• LogP: 4.99840

Purity/Quality:

99% ^*data from raw suppliers

Asenapinehydrochloride 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Saphris hydrochloride

There total 1 articles about Saphris hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate (85650-55-1) + asenapine (65576-45-6,65621-78-5) → trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole hydrochloride (1412458-61-7)

Guidance literature:

With hydrogenchloride; In water; ethyl acetate; for 0.75h; Product distribution / selectivity;

upstream raw materials:

trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate

asenapine

Refernces