Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside

Base Information Edit

Chemical Name:Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside
CAS No.:25420-97-7
Molecular Formula:C27H58N2O6SSi3
Molecular Weight:623.09
Hs Code.:
Mol file:25420-97-7.mol

Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside

Synonyms:2,3,4-Tri-O-triMethylsilyllincoMycin;Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside

Suppliers and Price of Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2,3,4-Tri-O-trimethylsilyllincomycin
50mg
$ 496.00

TRC
2,3,4-Tri-O-trimethylsilyllincomycin
500mg
$ 1390.00

Medical Isotopes, Inc.
2,3,4-Tri-O-trimethylsilyllincomycin
50 mg
$ 675.00

Total 1 raw suppliers

Chemical Property of Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside Edit

Chemical Property:

Boiling Point:620.4±55.0 °C(Predicted)
PKA:14.20±0.40(Predicted)
PSA：118.28000
Density:1.05±0.1 g/cm3(Predicted)
LogP:5.49880
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

2,3,4-Tri-O-trimethylsilyllincomycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Protected Lincomycin (L466200). An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23 S rRNA. Inhibits bacterial protein synthesis. Antibacterial. Protected Lincomycin (L466200). An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.

Technology Process of Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside

There total 7 articles about Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2-pyrrolidinyl]carbonyl]aMino]-1-thio-2,3,4-tris-O-(triMethylsilyl)-D-erythro-α-D-galacto-octopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 75-77-4
chloro-trimethyl-silane

: 154-21-2
lincomycin

: 25420-97-7
2,3,4-tris-O-(trimethylsilyl)lincomycin

Guidance literature:: chloro-trimethyl-silane; lincomycin; With pyridine; 1,1,1,3,3,3-hexamethyl-disilazane; at 20 ℃; for 2h; Ice cooling;

With water; acetic acid; In methanol; at 20 ℃; for 16h;

With sodium hydrogencarbonate; In methanol; water;

Reference yield: 91.0%

: 75-77-4
chloro-trimethyl-silane

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 154-21-2
lincomycin

: 25420-97-7
2,3,4-tris-O-(trimethylsilyl)lincomycin

Guidance literature:: chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; lincomycin; With pyridine; at 20 ℃; Cooling with ice;

With acetic acid; In methanol; water; at 20 ℃; for 16h;

With sodium hydrogencarbonate; In methanol; water;