a-Naphthylammoniumchlorid

Base Information

• Chemical Name: a-Naphthylammoniumchlorid
• CAS No.: 552-46-5
• Molecular Formula: C10H9 N . Cl H
• Molecular Weight: 179.649
• Hs Code.: 2921.45
• Mol file: 552-46-5.mol

Synonyms:a-Naphthylammoniumchlorid;naphthalen-1-aminium chloride;NS00080377

Chemical Property of a-Naphthylammoniumchlorid

Chemical Property:

• Appearance/Colour: gray crystalline powder
• Vapor Pressure: 0.00108mmHg at 25°C
• Melting Point: 272 - 275 C
• Flash Point: 152.1 °C
• PSA: 26.02000
• Density: 1.137g/cm³
• LogP: 3.80520
• Storage Temp.: Store below +30°C.
• Sensitive.: Air Sensitive
• Solubility.: 37.7g/l
• Water Solubility.: Soluble in water, alcohol, ether
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 179.0501770
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

99.0%Min ^*data from raw suppliers

1-AminonaphthaleneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): UN NO.
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2[NH3+].[Cl-]
• Uses: Applied as a synthesis reagent.

Technology Process of a-Naphthylammoniumchlorid

There total 5 articles about a-Naphthylammoniumchlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methanol (67-56-1) + 1-(1-naphthyl)-3-phenyl-2,2-dichloroaziridine (31528-95-7) → methylene chloride (74-87-3) + Dimethyl ether (115-10-6,157621-61-9) + methyl 2-chloro-2-phenylethanoate (7476-66-6) + methyl 2-methoxy-2-phenylacetate (3558-61-0) + 1-naphthylamine hydrochloride (552-46-5)

Guidance literature:

Product distribution; Heating;

DOI:10.1021/jo01298a051

Reference yield:

1-amino-naphthalene (134-32-7) → 1-naphthylamine hydrochloride (552-46-5)

Guidance literature:

With hydrogenchloride; In ethanol;

DOI:10.1007/s10593-011-0661-z

Reference yield:

naphthalen-1-yl-(4,4,5,5-tetramethyl-[1,3]dioxolan-2-ylidene)-amine → 1-naphthylamine hydrochloride (552-46-5)

Guidance literature:

With hydrogenchloride; methanol; In diethyl ether; at 20 ℃; for 1h;

DOI:10.1021/ol0479951

upstream raw materials:

methanol

1-(1-naphthyl)-3-phenyl-2,2-dichloroaziridine

2,4-dichloro-3-naphthalen-1-yl-1,2,3,4-tetrahydro-naphtho[2,1-e][1,3,2,4]diazadiborinine

naphthalene

Downstream raw materials:

4-(1-naphthalenylazo)-1-naphthalenamine

1-Naphthyl isocyanate

1-acetamidonaphthalene

N-1-naphthalenyl-benzamide

Refernces

• 1、 Aksenov,Lyakhovnenko,Kugutov. "New method for the direct electrophilic amination of aromatic compounds and its use in the annelation of the pyrimidine ring". . p. 1262 - 1265. Retrieved 2011/10/09.
• 2、 Meilahn, Marcus K.,Pottorf, Richard S.. "Haloaziridines. 3. Methanolysis of Some gem-Dichloroaziridines". . p. 2004 - 2005. Retrieved 2007/10/02.