Azetidine

Base Information Edit

Chemical Name:Azetidine
CAS No.:503-29-7
Deprecated CAS:156423-81-3
Molecular Formula:C3H7N
Molecular Weight:57.0953
Hs Code.:29339990
European Community (EC) Number:207-963-8
UNII:37S883XDWR
DSSTox Substance ID:DTXSID8060117
Nikkaji Number:J79.636K
Wikipedia:Azetidine
Wikidata:Q425376
Metabolomics Workbench ID:54298
ChEMBL ID:CHEMBL2171713
Mol file:503-29-7.mol

Synonyms:1,3-propylenimine;azacyclobutane;azetidine;trimethylenimine

Suppliers and Price of Azetidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
Azetidine
5G
$ 429.00

TCI Chemical
Azetidine
1G
$ 124.00

Synthonix
Azetidine 95-98%
1g
$ 35.00

Sigma-Aldrich
Azetidine 98%
250mg
$ 115.00

Sigma-Aldrich
Azetidine 98%
1g
$ 288.00

Medical Isotopes, Inc.
Azetidine 98%
5 mg
$ 990.00

Matrix Scientific
Azetidine 97%
1g
$ 39.00

Chem-Impex
Azetidine,≥98%(GC)Hazmat ≥98%(GC)
5G
$ 491.11

Chemenu
Azetidine 95+%
1000g
$ 8448.00

Biosynth Carbosynth
Azetidine
5 g
$ 370.00

Total 108 raw suppliers

Chemical Property of Azetidine Edit

Chemical Property:

Appearance/Colour:clear colorless liquid
Melting Point:-70°C
Refractive Index:n20/D 1.432(lit.)
Boiling Point:64.9 °C at 760 mmHg
PKA:11.29(at 25℃)
Flash Point:?5°F
PSA：12.03000
Density:0.851 g/cm³
LogP:0.30850
Storage Temp.:2-8°C
Sensitive.:Moisture Sensitive/Air Sensiti
Water Solubility.:miscible
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:57.057849228
Heavy Atom Count:4
Complexity:17.2

Purity/Quality:

>95% ^*data from raw suppliers

Azetidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,C
Hazard Codes:F,C
Statements: 11-34
Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CNC1
Uses suzuki reaction Azetidine is involved in a high yielding palladium-catalyzed cross-coupling reaction with aryl bromides. Further, it is used in Ullmann type coupling reaction with iodonitroflourenes. In addition to this, it reacts with bis-(3-amino-propyl)-amine to prepare N,N'-bis-(3-amino-propyl)-propanediyldiamine using palladium as a catalyst.

Technology Process of Azetidine

There total 28 articles about Azetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 78797-58-7,78797-59-8,78797-62-3,36520-39-5,65546-09-0
azetidine hydrochloride

: 503-29-7
azetidine

Guidance literature:: With potassium hydroxide; In water; at 20 - 95 ℃; for 3h; Inert atmosphere;
DOI:10.1021/op700052u

Reference yield: 85.0%

: 78797-58-7,78797-59-8,78797-62-3,36520-39-5,65546-09-0
azetidine hydrochloride

: potassium hydroxide

: 503-29-7
azetidine

Guidance literature:: In water; at 90 ℃;
DOI:10.1021/ma901984d

Reference yield: 83.0%

: 107128-00-7
N-benzhydryl azetidine

: 503-29-7
azetidine

Guidance literature:: With hydrogenchloride; potassium hydroxide; hydrogen; palladium on activated charcoal; 1.) methanol, 60 deg C, 40 - 80 psi, 2 h, 2.) 100 deg C;