Quinoxaline-6-carboxylic acid ethyl ester

Base Information

• Chemical Name: Quinoxaline-6-carboxylic acid ethyl ester
• CAS No.: 6924-72-7
• Molecular Formula: C₁₁H₁₀N₂O₂
• Molecular Weight: 202.213
• Hs Code.: 2933990090
• Mol file: 6924-72-7.mol

Synonyms:Ethyl quinoxaline-6-carboxylate;Quinoxaline-6-carboxylic acid ethyl ester;6-(Ethoxycarbonyl)quinoxaline

Chemical Property of Quinoxaline-6-carboxylic acid ethyl ester

Chemical Property:

• PSA: 52.08000
• LogP: 1.80650
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

Ethylquinoxaline-6-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoxaline-6-carboxylic acid ethyl ester

There total 2 articles about Quinoxaline-6-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3,4-diaminobenzoate (37466-90-3) → Chinoxalin-6-carbonsaeure-ethylester (6924-72-7)

Guidance literature:

With Glyoxal;

DOI:10.1039/jr9560002058

Reference yield:

ethyl 4-amino-3-nitrobenzoate (76918-64-4) → Chinoxalin-6-carbonsaeure-ethylester (6924-72-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Raney nickel; methanol / Hydrogenation

2: disodium-salt of/the/ 1,2-dihydroxy-ethane-1,2-disulfonic acid; H₂O

With methanol; water; nickel; glyoxal sodium bisulfite;

DOI:10.1039/jr9560002058

Reference yield:

Chinoxalin-6-carbonsaeure-ethylester (6924-72-7) → quinoxaline-6-carboxylic acid (6925-00-4)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

ethyl 3,4-diaminobenzoate

ethyl 4-amino-3-nitrobenzoate

Downstream raw materials:

quinoxaline-6-carboxylic acid