2,4-Dihydroxy-3,5-dibromopyridine

Base Information

• Chemical Name: 2,4-Dihydroxy-3,5-dibromopyridine
• CAS No.: 80791-78-2
• Molecular Formula: C5H3Br2NO2
• Molecular Weight: 268.89
• Mol file: 80791-78-2.mol

Synonyms:2,4-Dihydroxy-3,5-dibromopyridine

Chemical Property of 2,4-Dihydroxy-3,5-dibromopyridine

Chemical Property:

• PSA: 53.35000
• LogP: 2.01780

Purity/Quality:

97% ^*data from raw suppliers

2,4-DIHYDROXY-3,5-DIBROMOPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Dihydroxy-3,5-dibromopyridine

There total 3 articles about 2,4-Dihydroxy-3,5-dibromopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-hydroxy-2-pyridone (626-03-9) → 3,5-dibromo-4-hydroxy-2-pyridinone (80791-78-2)

Guidance literature:

With hydrogen bromide; bromine; In water; for 72h;

Reference yield: 72.0%

3-deazauracil (626-03-9,84719-31-3) → 3,5-dibromo-2,4-dihydroxypyridine (80791-78-2)

Guidance literature:

With bromine; In hydrogen bromide; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2004.07.035

Reference yield:

→ 3,5-dibromo-2,4-dihydroxypyridine (80791-78-2)

Guidance literature:

With bromine;

upstream raw materials:

3-deazauracil

4-hydroxy-2-pyridone

Downstream raw materials:

3-bromo-2,4-dichloro-pyridine

2,5-dibromo-[4]pyridylamine

1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-4-hydroxy-2-pyridinone

5-bromo-4-hydroxy-2-pyridinone

Refernces

• 1、 Brand, Silke,Roy, Sayantani,Schr?der, Peter,Rathmer, Bernd,Roos, Jessica,Kapoor, Shobhna,Patil, Sumersing,Pommerenke, Claudia,Maier, Thorsten,Janning, Petra,Eberth, Sonja,Steinhilber, Dieter,Schade, Dennis,Schneider, Gisbert,Kumar, Kamal,Ziegler, Slava,Waldmann, Herbert. "Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways". . p. 1095 - 23,1106. Retrieved 2018/06/11.
• 2、 Irlapati, Nageswara Rao,Adlington, Robert M.,Conte, Aurelia,Pritchard, Gareth J.,Marquez, Rodolfo,Baldwin, Jack E.. "Total synthesis of pyridovericin". . p. 9307 - 9317. Retrieved 2007/10/03.