Technology Process of 1-phenyl-1,3,5-hexatriyne
There total 14 articles about 1-phenyl-1,3,5-hexatriyne which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium hydroxide;
In
methanol;
at 10 - 20 ℃;
1.) 10 deg C and 20 deg C, 1 h, 2.) MeOH;
DOI:10.1021/jo00246a003
- Guidance literature:
-
With
potassium carbonate;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 4h;
DOI:10.1002/ejoc.200700630
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 2 h / 50 °C / Inert atmosphere
2.1: silver fluoride / acetonitrile; water / 0.33 h
2.2: 3 h
3.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 2 h / 50 °C / Inert atmosphere
4.1: potassium carbonate / dichloromethane; methanol / 1 h / 20 °C
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; silver fluoride; potassium carbonate; triethylamine;
In
methanol; dichloromethane; water; acetonitrile;
