Technology Process of 2,3,3-Triphenylprop-2-enoic acid
There total 22 articles about 2,3,3-Triphenylprop-2-enoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl α,α-dibromobenzeneacetate;
With
naphthalene; lithium;
In
tetrahydrofuran;
at -78 - 20 ℃;
benzophenone;
In
tetrahydrofuran;
at 20 ℃;
DOI:10.1021/jo0497813
- Guidance literature:
-
2,3,3-triphenylacrylonitrile;
With
potassium hydroxide;
In
water; ethylene glycol;
at 185 ℃;
for 48h;
With
hydrogenchloride;
In
water; ethylene glycol;
at 20 ℃;
pH=5 - 6;
DOI:10.1039/c3ra23188g
- Guidance literature:
-
phenylmagnesium bromide; diphenyl acetylene;
With
nickel dichloride;
In
tetrahydrofuran; toluene;
at 60 ℃;
for 2h;
Schlenk technique;
Inert atmosphere;
carbon dioxide;
In
tetrahydrofuran; toluene;
at 20 ℃;
for 0.5h;
under 760.051 Torr;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/acs.orglett.8b01693
