methyl 2,3,3-triphenylacrylate

Base Information

• Chemical Name: methyl 2,3,3-triphenylacrylate
• CAS No.: 181224-77-1
• Molecular Formula: C₂₂H₁₈O₂
• Molecular Weight: 314.384
• Mol file: 181224-77-1.mol

Synonyms:methyl 2,3,3-triphenylacrylate

Chemical Property of methyl 2,3,3-triphenylacrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3,3-triphenylacrylate

There total 6 articles about methyl 2,3,3-triphenylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2,3,3-triphenylacrylic acid (4452-05-5) + methyl iodide (74-88-4) → methyl 2,3,3-triphenylacrylate (181224-77-1)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 3h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.8b01693

Reference yield: 72.0%

Diphenylmethane (101-81-5) + Methyl phenyldiazoacetate (22979-35-7) → methyl 2,3,3-triphenylacrylate (181224-77-1)

Guidance literature:

Diphenylmethane; With 2,3-dicyano-5,6-dichloro-p-benzoquinone; iron(II) chloride; In 1,2-dichloro-ethane; at 90 ℃; for 0.5h; Schlenk technique; Inert atmosphere; Sealed tube;

Methyl phenyldiazoacetate; In 1,2-dichloro-ethane; for 0.5h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1039/c9cc01060b

Reference yield: 66.0%

tributylphenylstannane (960-16-7) + phenylpropynoic acid methyl ester (4891-38-7) → methyl 2,3,3-triphenylacrylate (181224-77-1)

Guidance literature:

With palladium dichloride; In 1,4-dioxane; at 60 ℃; for 2h;

DOI:10.1246/cl.1996.811

upstream raw materials:

Dichlorodiphenylmethane

benzeneacetic acid methyl ester

tributylphenylstannane

phenylpropynoic acid methyl ester

Downstream raw materials:

2,3-diphenyl-2,3-epoxy-1-indanone

2,3-diphenyl-1H-inden-1-one

Refernces

• 1、 Shi, Jiang-Ling,Luo, Qinyu,Yu, Weizhi,Wang, Bo,Shi, Zhang-Jie,Wang, Jianbo. "Fe(II)-Catalyzed alkenylation of benzylic C-H bonds with diazo compounds". supporting information. p. 4047 - 4050. Retrieved 2019/04/10.