L-QUEBRACHITOL

Base Information

• Chemical Name: L-QUEBRACHITOL
• CAS No.: 642-38-6
• Molecular Formula: C7H14 O6
• Molecular Weight: 194.185
• Hs Code.: 2906.13
• Mol file: 642-38-6.mol

Synonyms:Inositol,2-O-methyl- (6CI,7CI); Inositol, 2-O-methyl-, L-chiro- (8CI); (-)-Quebrachitol;2-O-Methyl-L-chiro-inositol; Brahol; L-(-)-2-O-Methylinositol; L-Quebrachitol;NSC 26254; Quebrachit; Quebrachitol; Quebrachitol, (-)-

Chemical Property of L-QUEBRACHITOL

Chemical Property:

• Appearance/Colour: white to off-white crystals
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 189 - 192 C
• Refractive Index: 1.572
• Boiling Point: 317.2 °C at 760 mmHg
• PKA: 12.98±0.70(Predicted)
• Flash Point: 145.6 °C
• PSA: 110.38000
• Density: 1.56 g/cm³
• LogP: -3.18050
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Water (Sparingly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-Quebrachitol| ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Not regulated
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-QUEBRACHITOL

There total 50 articles about L-QUEBRACHITOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4/6-O-methyl-myo-inositol 1,3,5-monoorthoformate → 4-O-methyl-myo-inositol (484-68-4,484-69-5,484-71-9,523-92-2,642-38-6,3559-00-0,3564-07-6,6090-97-7,7586-49-4,7600-53-5,10284-63-6,17405-65-1,22350-68-1,23887-12-9,32934-27-3,35688-46-1,56782-15-1,58769-21-4,60537-25-9,64314-40-5,74560-60-4,103773-59-7,111059-09-7,115888-70-5,144902-49-8)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 5h;

DOI:10.1039/b417757f

Reference yield: 100.0%

DL-1,3-di-O-benzoyl-4-O-methyl-chiro-inositol (111015-74-8,138258-56-7) → 4-O-methyl-myo-inositol (484-68-4,484-69-5,484-71-9,523-92-2,642-38-6,3559-00-0,3564-07-6,6090-97-7,7586-49-4,7600-53-5,10284-63-6,17405-65-1,22350-68-1,23887-12-9,32934-27-3,35688-46-1,56782-15-1,58769-21-4,60537-25-9,64314-40-5,74560-60-4,103773-59-7,111059-09-7,115888-70-5,144902-49-8)

Guidance literature:

With water; triethylamine; In methanol; for 3h; Ambient temperature;

DOI:10.1016/S0040-4020(01)81025-5

Reference yield: 100.0%

DL-1,2-di-O-methyl-chiro-inositol (111015-73-7) → 4-O-methyl-myo-inositol (484-68-4,484-69-5,484-71-9,523-92-2,642-38-6,3559-00-0,3564-07-6,6090-97-7,7586-49-4,7600-53-5,10284-63-6,17405-65-1,22350-68-1,23887-12-9,32934-27-3,35688-46-1,56782-15-1,58769-21-4,60537-25-9,64314-40-5,74560-60-4,103773-59-7,111059-09-7,115888-70-5,144902-49-8)

Guidance literature:

With water; triethylamine; In methanol; for 3h; Ambient temperature;

DOI:10.1016/S0040-4020(01)81025-5

upstream raw materials:

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside

(4S,5R,6S)-4,5,6-tris-benzyloxycyclohex-2-en-1-one

1-O-Allyl-2,3,4-tri-O-benzyl-D-chiro-inositol

(1R,2R,3S)-tris(phenylmethoxy)-6S-hydroxy-cyclohex-4-ene

Downstream raw materials:

2,3,4,5,6-Penta-O-acetyl-1-O-methyl-myo-inositol

L-1,3,4,5,6-penta-O-benzoyl-2-O-methyl-chiro-inositol

bornesitol

3-O-Methyl-D-myo-inosose-⁽¹⁾

Refernces

• 1、 Jung, Pierre M. J.,Motherwell, William B.,Williams, Alvin S.. "Stereochemical observations on the bromate induced monobromopentahydroxylation of benzene by catalytic photoinduced charge transfer osmylation. A concise synthesis of (±)-pinitol". . p. 1283 - 1284. Retrieved 2007/10/03.
• 2、 Jaramillo,Martin-Lomas. "Approaches to the synthesis of glycosyl phosphatidyl inositols. Enantioselective synthesis of optically active chiro- and myo-inositols". . p. 2501 - 2504. Retrieved 2007/10/02.