9-Decyn-1-ol

Base Information

• Chemical Name: 9-Decyn-1-ol
• CAS No.: 17643-36-6
• Molecular Formula: C10H18O
• Molecular Weight: 154.252
• Hs Code.: 2905290000
• DSSTox Substance ID: DTXSID6066236
• Nikkaji Number: J693.655E
• Wikidata: Q81992823
• Mol file: 17643-36-6.mol

Synonyms:9-Decyn-1-ol;dec-9-yn-1-ol;17643-36-6;10-Hydroxy-1-decyne;SCHEMBL330175;DTXSID6066236;MFCD00049199;AKOS005137925;AS-47819;HY-130985;CS-0119650;D3710;FT-0651796;F16255;A812184

Chemical Property of 9-Decyn-1-ol

Chemical Property:

• Vapor Pressure: 0.0113mmHg at 25°C
• Melting Point: 1.9°C (estimate)
• Refractive Index: 1.4540-1.4580
• Boiling Point: 92 °C / 4mmHg
• PKA: 15.19±0.10(Predicted)
• Flash Point: 171.8°C
• PSA: 20.23000
• Density: 0.87
• LogP: 2.34260
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 7
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 109

Purity/Quality:

98%,99%, ^*data from raw suppliers

9-?Decyn-?1-?ol(94%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C#CCCCCCCCCO
• Uses: 9-?Decyn-?1-?ol is a building block used in a variety of synthetic assays, such as the synthesis of macrolactones bearing 1,3-butadiynes and the microwave-assisted synthesis of disubstituted heterocyclic compounds.

Technology Process of 9-Decyn-1-ol

There total 27 articles about 9-Decyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-decyn-1-ol (4117-14-0) → 9-decyn-1-ol (17643-36-6)

Guidance literature:

With 1,2-diaminoethane sodium; ethylenediamine; at 55 ℃; for 1h;

Reference yield: 91.4%

3-decyn-1-ol (51721-39-2) → 9-decyn-1-ol (17643-36-6)

Guidance literature:

With sodium hydride; Trimethylenediamine; at 10 - 100 ℃; for 2h;

DOI:10.1016/j.jfluchem.2004.09.017

Reference yield: 85.0%

4-decyne-1-ol (69222-06-6) → 9-decyn-1-ol (17643-36-6)

Guidance literature:

With sodium amide; In various solvent(s); at 80 ℃; for 2h;

DOI:10.1016/S0040-4020(01)87295-1

upstream raw materials:

3-decyn-1-ol

methyl dec-9-ynoate

2-decyn-1-ol

4-decyne-1-ol

Downstream raw materials:

dec-9-ynoic acid

(12S,17S,Z)-12-((tert-butyldiphenylsilyl)oxy)-17-ethyloxacycloheptadeca-10-en-13,15-diyn-2-one

(Z)-11-((4-methoxybenzyl)oxy)undec-2-en-1-ol

Refernces

• 1、 Durand, Sandrine,Parrain, Jean-Luc,Santelli, Maurice. "A large scale and concise synthesis of γ-linolenic acid from 4- chlorobut-2-yn-1-ol". . p. 1015 - 1018. Retrieved 1998.
• 2、 Grodner, Jacek,Golebiewski, W. Marek,Willis, Michael C.,Osborne, James D.,Gucma, Miros?aw. "The first stereoselective synthesis of a dithiane derivative of the C18 β-diketodiene system proposed for an active compound isolated from Cantharellus cibarius (chanterelle)". . p. 1181 - 1189. Retrieved 2015.
• 3、 Itoh, Seiji,Kuwahara, Shigefumi,Hasegawa, Morifumi,Kodama, Osamu. "Synthesis of the (17R)- and (17S)-isomers of volicitin, an elicitor of plant volatiles contained in the oral secretion of the beet armyworm". . p. 1591 - 1596. Retrieved 2002.
• 4、 Sun, Wei-Chuan,Prestwich, Glenn D.. "Partially fluorinated analogs of (Z)-9-dodecenyl acetate: Probes for pheromone hydrophobiclty requirements". . p. 801 - 804. Retrieved 1990.
• 5、 Kimmel, T.,Becker, D.. "New Procedures for Preparation of Potassium 3-Aminopropylamide". . p. 2494 - 2496. Retrieved 1984.
• 6、 Takai, Katsuki,Takagi, Toshiyuki,Baba, Teruhiko,Kanamori, Toshiyuki. "Highly fluorinated C18 fatty acids: Synthesis and interfacial properties". . p. 1959 - 1964. Retrieved 2004.
• 7、 Ahn, Deok Kyun,Kang, Young Woo,Woo, Sang Kook. "Oxidative Deprotection of p-Methoxybenzyl Ethers via Metal-Free Photoredox Catalysis". . p. 3612 - 3623. Retrieved 2019/03/11.