4-O-beta-D-Glucopyranosyl-D-glucose

Base Information

• Chemical Name: 4-O-beta-D-Glucopyranosyl-D-glucose
• CAS No.: 528-50-7
• Molecular Formula: C12H22O11
• Molecular Weight: 342.3
• Hs Code.: 29400090
• European Community (EC) Number: 208-436-5
• Wikipedia: Cellobiose
• Mol file: 528-50-7.mol

Synonyms:cellobiose;Cellose;D-Cellobiose;D-(+)-Cellobiose;D-Glucosyl-beta-(1-4)-D-glucose;4-O-beta-D-Glucopyranosyl-D-glucose;4-beta-D-glucopyranosyl-D-glucopyranose;D-Glucose, 4-O-.beta.-D-glucopyranosyl-;528-50-7

Chemical Property of 4-O-beta-D-Glucopyranosyl-D-glucose

Chemical Property:

• Appearance/Colour: crystalline
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 239 °C (dec.)(lit.)
• Refractive Index: 34 ° (C=8, H2O)
• Boiling Point: 667.9 °C at 760 mmHg
• PKA: 12.39±0.20(Predicted)
• Flash Point: 357.8 °C
• PSA: 189.53000
• Density: 1.76 g/cm³
• LogP: -5.39720
• Storage Temp.: Store at RT.
• Solubility.: Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly)
• Water Solubility.: Soluble in water (1 g/8ml). Insoluble in ether and ethanol.
• XLogP3: -4.7
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 4
• Exact Mass: 342.11621151
• Heavy Atom Count: 23
• Complexity: 382

Purity/Quality:

BR，98% ^*data from raw suppliers

D-Cellobiose ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Disaccharides
• Canonical SMILES: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)O)CO)O)O)O)O
• Isomeric SMILES: C([C@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@@H](O[C@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O
• Uses: D-(+)-Cellobiose is commonly used as a carbohydrate indicator for intestinal permeability in Crohn’s disease and malabsorption syndrome. When treated with sulfuric acid and acetic anhydride, cellulose generates cellobiose tetraacetate, which is soluble in nonpolar solvents and cannot engage in hydrogen bonding. Bacteriology. D-(+)-Cellobiose is used to differentiate bacteria based on carbohydrate fermentation abilities. It is a β-glucosidase substrate. Also used as as a chemical raw material and for foods, as a low-sweetness sugar.

Technology Process of 4-O-beta-D-Glucopyranosyl-D-glucose

There total 28 articles about 4-O-beta-D-Glucopyranosyl-D-glucose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

Pinus cellulose → cellotriose (33404-34-1) + 5-hydroxymethyl-2-furfuraldehyde (67-47-0) + D-glucose (50-99-7) + cellotetraose (6918-41-8,34612-38-9,38819-01-1,51327-76-5,51841-90-8,59862-03-2,60755-09-1,60755-10-4,61237-57-8,70399-65-4,72165-13-0,73062-57-4,95336-74-6,102031-44-7,107595-47-1,146491-17-0,150668-99-8) + cellobiose (528-50-7)

Guidance literature:

Pinus cellulose; With choline chloride; oxalic acid; 1-butyl-3-methylimidazolium chloride; at 120 ℃; for 6h;

With water; at 120 ℃; for 4h;

DOI:10.1002/open.201900283

Reference yield: 48.0%

Eucalyptus cellulose → cellotriose (33404-34-1) + 5-hydroxymethyl-2-furfuraldehyde (67-47-0) + D-glucose (50-99-7) + cellobiose (528-50-7)

Guidance literature:

Eucalyptus cellulose; With choline chloride; oxalic acid; 1-butyl-3-methylimidazolium chloride; at 120 ℃; for 6h;

With water; at 120 ℃; for 4h;

DOI:10.1002/open.201900283

Reference yield: 46.0%

Pinus cellulose, unbleached → cellotriose (33404-34-1) + 5-hydroxymethyl-2-furfuraldehyde (67-47-0) + D-glucose (50-99-7) + cellotetraose (6918-41-8,34612-38-9,38819-01-1,51327-76-5,51841-90-8,59862-03-2,60755-09-1,60755-10-4,61237-57-8,70399-65-4,72165-13-0,73062-57-4,95336-74-6,102031-44-7,107595-47-1,146491-17-0,150668-99-8) + cellobiose (528-50-7)

Guidance literature:

Pinus cellulose, unbleached; With choline chloride; oxalic acid; 1-butyl-3-methylimidazolium chloride; at 120 ℃; for 6h;

With water; at 120 ℃; for 4h;

DOI:10.1002/open.201900283

upstream raw materials:

D-glucose

water

cellulose

microcrystalline cellulose

Downstream raw materials:

1,2,4,5-tetrahydroxy-pentanecarboxylic acid

formaldehyd

formic acid

methylammonium carbonate

Refernces

• 1、 Whistler,Smart. "-". . p. 1916. Retrieved 1953.
• 2、 Bodachivskyi, Iurii,Kuzhiumparambil, Unnikrishnan,Bradley G. Williams. "High Yielding Acid-Catalysed Hydrolysis of Cellulosic Polysaccharides and Native Biomass into Low Molecular Weight Sugars in Mixed Ionic Liquid Systems". . p. 1316 - 1324. Retrieved 2019/11/11.
• 3、 Yuan, Ye,Xu, Fenghua,Yao, Jianzhuang,Hu, Yanho,Wang, Jiao,Zhao, Tianjiao,Zhou, Yifa,Gao, Juan. "Cloning, expression and biochemical characterization of a GH1 β-glucosidase from Cellulosimicrobium cellulans". . p. 362 - 371. Retrieved 2017/11/03.