Diacetic acid 1α,4α-cyclohexylene ester

Base Information

• Chemical Name: Diacetic acid 1α,4α-cyclohexylene ester
• CAS No.: 42742-00-7
• Molecular Formula: C10H16O4
• Molecular Weight: 200.235
• Mol file: 42742-00-7.mol

Synonyms:1,4-diacetoxycyclohexane;cis-1,4-Diacetoxycyclohexane;1,4-Diacetoxy-cyclohexan;cyclohexane-1,4-diyl diacetate;

Chemical Property of Diacetic acid 1α,4α-cyclohexylene ester

Chemical Property:

• Vapor Pressure: 0.0226mmHg at 25°C
• Boiling Point: 249.7°C at 760 mmHg
• Flash Point: 115.4°C
• PSA: 52.60000
• Density: 1.09g/cm³
• LogP: 1.42380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diacetic acid 1α,4α-cyclohexylene ester

There total 15 articles about Diacetic acid 1α,4α-cyclohexylene ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

1,4-Cyclohexanediol (556-48-9) + acetic anhydride (108-24-7) → 1,4-diacetoxycyclohexane (6289-83-4,42742-00-7,19843-75-5) + (4-hydroxycyclohexyl) acetate (58512-50-8)

Guidance literature:

With pyridine; In dichloromethane; for 8h; Ambient temperature;

DOI:10.1016/S0040-4020(01)86873-3

Reference yield: 17.2%

cyclohexane (110-82-7,25012-93-5) → N-cyclohexylacetamide (1124-53-4) + optically inactive 1.3-diacetoxy-cyclohexane (6939-74-8) + cyclohexyl acetate (622-45-7) + 1,4-diacetoxycyclohexane (6289-83-4,42742-00-7,19843-75-5) + 1,2-diacetoxy-cyclohexane (2276-46-2)

Guidance literature:

With ferrous perchlorate; dihydrogen peroxide; acetonitrile; at 30 ℃; Product distribution;

Reference yield:

1,4-Cyclohexanediol (556-48-9) + acetic anhydride (108-24-7) → 1,4-diacetoxycyclohexane (6289-83-4,42742-00-7,19843-75-5) + 4-(1-oxoethyl)-1-cyclohexanone (5034-21-9) + 1,4-Cyclohexanedione (637-88-7)

Guidance literature:

at 10 - 15 ℃; substances of uncertain configuration;

upstream raw materials:

cyclohexane

1,4-Cyclohexanediol

acetic anhydride

acetyl chloride

Downstream raw materials:

trans-1,4-dibromocyclohexane

trans-1,4-dichlorocyclohexane

cis-1,4-cyclohexanediol

cis-1-Acetoxy-cyclohexanol-⁽⁴⁾

Refernces

• 1、 Nakano, Yasushi,Sakaguchi, Satoshi,Ishii, Yasutaka. "Meerwein-Ponndorf-Verley-type reductive acetylation of carbonyl compounds to acetates by lanthanide complexes in the presence of isopropenyl acetate". . p. 1565 - 1569. Retrieved 2007/10/03.
• 2、 Endo, Katsuya,Seya, Kazuhiko,Hikino, Hiroshi. "STEREOSTRUCTURE OF RENGYOL AND ISORENGYOL, PHENYLETHANOIDS OF FORSYTHIA SUSPENSA". . p. 2681 - 2688. Retrieved 2007/10/02.