2,5-Dinitrofuran

Base Information

• Chemical Name: 2,5-Dinitrofuran
• CAS No.: 826-03-9
• Molecular Formula: C4H2N2O5
• Molecular Weight: 158.07
• NSC Number: 53253
• DSSTox Substance ID: DTXSID70231905
• Nikkaji Number: J75.475G
• Wikidata: Q83112901
• Mol file: 826-03-9.mol

Synonyms:2,5-Dinitrofuran;826-03-9;FURAN, 2,5-DINITRO-;NSC 53253;BRN 0155563;2,5-Dinitro-furan;Furan,5-dinitro-;NSC53253;WLN: T5OJ BNW ENW;C4H2N2O5;SCHEMBL15200988;DTXSID70231905;C4-H2-N2-O5;NSC-53253;LS-70203

Chemical Property of 2,5-Dinitrofuran

Chemical Property:

• Vapor Pressure: 0.0258mmHg at 25°C
• Boiling Point: 255.7°C at 760 mmHg
• Flash Point: 108.4°C
• PSA: 104.78000
• Density: 1.648g/cm³
• LogP: 2.14240
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 157.99637117
• Heavy Atom Count: 11
• Complexity: 162

Purity/Quality:

99% ^*data from raw suppliers

2,5-dinitro-Furan 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(OC(=C1)[N+](=O)[O-])[N+](=O)[O-]

Technology Process of 2,5-Dinitrofuran

There total 2 articles about 2,5-Dinitrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-sulfofuran-2-carboxylic acid (87299-57-8) → 5-nitro-2-furoic acid (645-12-5) + 2,5-dinitrofuran (826-03-9)

Guidance literature:

With nitric acid;

DOI:10.1021/jo01371a003

Reference yield:

5-sulfofuran-2-carboxylic acid (87299-57-8) + nitric acid (7697-37-2,78989-43-2) → 5-nitro-2-furoic acid (645-12-5) + 2,5-dinitrofuran (826-03-9)

Guidance literature:

DOI:10.1246/bcsj.27.398 DOI:10.1021/jo01371a003

Reference yield:

2,5-dinitrofuran (826-03-9) + N-tosyl-3-butenylamine (10285-80-0) → N-but-3-enyl-4-methyl-N-(5-nitrofuran-2-yl)benzenesulfonamide (208335-39-1)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) THF, room temperature, 30 min, 2.) THF, room temperature, 3.5 h;

DOI:10.1021/jo980008f

upstream raw materials:

5-sulfofuran-2-carboxylic acid

nitric acid

Downstream raw materials:

N-but-3-enyl-4-methyl-N-(5-nitrofuran-2-yl)benzenesulfonamide

N-pent-4-enyl-4-methyl-N-(5-nitrofuran-2-yl)benzenesulfonamide