Technology Process of C13H18O2
There total 12 articles about C13H18O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Porcine pancreas lipase type II;
In
tert-butyl methyl ether;
at 20 ℃;
optical yield given as %ee;
enantioselective reaction;
Enzymatic reaction;
DOI:10.1016/j.tetasy.2011.03.012
- Guidance literature:
-
With
Pseudomonas cepacia lipase;
In
tert-butyl methyl ether;
at 20 ℃;
optical yield given as %ee;
enantioselective reaction;
Enzymatic reaction;
DOI:10.1016/j.tetasy.2011.03.012
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diethyl ether / 3.5 h / 0 - 20 °C / Inert atmosphere
1.2: Cooling with ice
2.1: toluene-4-sulfonic acid; hydroquinone / benzene / Reflux; Azeotropic water removal
3.1: dimethylsulfide borane complex / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
3.2: 1 h / 20 - 40 °C
3.3: 20 - 30 °C
4.1: Porcine pancreas lipase type II / tert-butyl methyl ether / 20 °C / Enzymatic reaction
With
Porcine pancreas lipase type II; dimethylsulfide borane complex; toluene-4-sulfonic acid; hydroquinone;
In
tetrahydrofuran; diethyl ether; tert-butyl methyl ether; benzene;
DOI:10.1016/j.tetasy.2011.03.012