Alprazolam

Base Information Edit

Chemical Name:Alprazolam
CAS No.:28981-97-7
Molecular Formula:C17H13ClN4
Molecular Weight:308.77
Hs Code.:2933910000
European Community (EC) Number:432-090-6,249-349-2
NSC Number:760140
UNII:YU55MQ3IZY
DSSTox Substance ID:DTXSID4022577
Nikkaji Number:J9.279G
Wikipedia:Alprazolam
Wikidata:Q319877
NCI Thesaurus Code:C227
RXCUI:596
Pharos Ligand ID:8RW91QB8HPUC
Metabolomics Workbench ID:42765
ChEMBL ID:CHEMBL661
Mol file:28981-97-7.mol

Synonyms:Alprazolam;Alprazolan;Alprox;Apo Alpraz;Apo-Alpraz;Cassadan;D-65MT;D65MT;Esparon;Kalma;Novo Alprazol;Novo-Alprazol;Nu Alpraz;Nu-Alpraz;Ralozam;Tafil;Trankimazin;U-31,889;U31,889;Xanax

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Alprazolam Edit

Chemical Property:

Appearance/Colour:white crystalline solid
Vapor Pressure:1.77E-10mmHg at 25°C
Melting Point:228-228.5 °C
Refractive Index:1.71
Boiling Point:508.959 °C at 760 mmHg
PKA:2.37±0.40(Predicted)
Flash Point:261.609 °C
PSA：43.07000
Density:1.369 g/cm³
LogP:3.01570
Storage Temp.:2-8°C
Solubility.:H2O: insoluble
Water Solubility.:70mg/L(ambient temperature)
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:308.0828741
Heavy Atom Count:22
Complexity:434

Purity/Quality:

Safty Information:

Pictogram(s): Xn,T,F
Hazard Codes:Xn,T,F
Statements: 22-39/23/24/25-23/24/25-11
Safety Statements: 36-45-36/37-16-7

MSDS Files:: SDS file from LookChem

Useful:

Drug Classes:Benzodiazepines, Antianxiety Agents
Canonical SMILES:CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
Recent ClinicalTrials:Licorice Botanical Dietary Supplements - Metabolism and Safety in Women
Recent EU Clinical Trials:A Phase I/II, 2-Arm, Open Label, Single Centre Study to Investigate the Safety and Effect of Oral GABA Therapy on β-cell Regeneration in Type 1-diabetes Patients
Recent NIPH Clinical Trials:A study to test the safety and tolerability of Staccato alprazolam in study participants 12 years of age and older with epilepsy
Description Alprazolam (Item No. 14255) is an analytical reference material categorized as a benzodiazepine. Alprazolam is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
Uses Controlled substance (depressant). Anxiolytic Atorvastatin metabolite
Therapeutic Function Tranquilizer

Technology Process of Alprazolam

There total 23 articles about Alprazolam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%