methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate

Base Information

• Chemical Name: methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate
• CAS No.: 1036273-12-7
• Molecular Formula: C₉H₆ClF₃O₂
• Molecular Weight: 238.594
• Mol file: 1036273-12-7.mol

Synonyms:methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate

Chemical Property of methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate

There total 1 articles about methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 2,4,5-trifluoromandelate (1036273-10-5) → methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate (1036273-12-7)

Guidance literature:

With thionyl chloride; at 80 ℃; Product distribution / selectivity;

Reference yield: 93.0%

methyl 2-(2,4,5-trifluorophenyl)-2-chloroacetate (1036273-12-7) → 2,4,5-trifluorophenylacetic acid methyl ester (1036273-20-7)

Guidance literature:

With iron; acetic acid; at 60 ℃; for 8h; Product distribution / selectivity;

upstream raw materials:

methyl 2,4,5-trifluoromandelate

Downstream raw materials:

2,4,5-trifluorophenylacetic acid methyl ester

Refernces