6-Pteridinemethanol, 2-amino-7,8-dihydro-4-hydroxy-

Base Information

• Chemical Name: 6-Pteridinemethanol, 2-amino-7,8-dihydro-4-hydroxy-
• CAS No.: 3672-03-5
• Molecular Formula: C7H9 N5 O2
• Molecular Weight: 195.181
• Mol file: 3672-03-5.mol

Synonyms:4(1H)-Pteridinone,2-amino-7,8-dihydro-6-(hydroxymethyl)- (9CI); 6-Pteridinemethanol,2-amino-7,8-dihydro-4-hydroxy- (7CI,8CI);2-Amino-4-hydroxy-6-(hydroxymethyl)-7,8-dihydropteridine;2-Amino-4-hydroxy-6-(hydroxymethyl)dihydropteridine;2-Amino-7,8-dihydro-4-hydroxy-6-(hydroxymethyl)pteridine;6-(Hydroxymethyl)-7,8-dihydropterin; 7,8-Dihydro-6-(hydroxymethyl)pterin

Chemical Property of 6-Pteridinemethanol, 2-amino-7,8-dihydro-4-hydroxy-

Chemical Property:

• Vapor Pressure: 1.37E-07mmHg at 25°C
• Boiling Point: 387.1°Cat760mmHg
• Flash Point: 187.9°C
• PSA: 117.38000
• Density: 1.98g/cm³
• LogP: -1.24160

Purity/Quality:

99%, ^*data from raw suppliers

2-amino-7,8-dihydro-6-(hydroxymethyl)-4(3H)-Pteridinone 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Pteridinemethanol, 2-amino-7,8-dihydro-4-hydroxy-

There total 2 articles about 6-Pteridinemethanol, 2-amino-7,8-dihydro-4-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dihydro-7,8-D-neopterine (1218-98-0) → 7,8-dihydro-6-(hydroxymethyl)pterin (3672-03-5) + Glycolaldehyde (141-46-8)

Guidance literature:

dihydroneopterin aldolase; pH=8.3; Further Variations:; Catalysts; Enzyme kinetics; Product distribution; Enzymatic reaction;

DOI:10.1021/ja063455i

Reference yield:

6-(hydroxymethyl)pterin (712-29-8) → 7,8-dihydro-6-(hydroxymethyl)pterin (3672-03-5)

Guidance literature:

With potassium hydroxide; zinc; 1.) water, room temp., in dark, 5 min; 2.) 55 deg C, 1 min;

DOI:10.1021/ac00260a004

Reference yield:

7,8-dihydro-6-(hydroxymethyl)pterin (3672-03-5) + salicylic acid (69-72-7,25496-36-0,8052-31-1) → 2,5-dihydroxybenzoic acid. (490-79-9)

Guidance literature:

With iron(III) sulfate; ethylenediaminetetraacetic acid; In phosphate buffer; at 20 ℃; pH=7.2; Further Variations:; without/with Fe(3+); Kinetics;

DOI:10.1002/(SICI)1522-2675(20000510)83:5<954::AID-HLCA954>3.0.CO;2-9

upstream raw materials:

6-(hydroxymethyl)pterin

dihydro-7,8-D-neopterine

Downstream raw materials:

2,5-dihydroxybenzoic acid.

6-hydroxymethyl-7,8-pterin pyrophosphate

6-hydroxymethyl-7,8-dihydro-pterin pyrophosphate

(6S,S)-5,6,7,8-tetrahydrofolic acid

Refernces

• 1、 Lunte, Craig E.,Kissinger, Peter T.. "Determination of Pterins in Biological Samples by Liquid Chromatography/Electrochemistry with a Dual-Electrode Detector". . p. 1458 - 1462. Retrieved 2007/10/02.