Boc-d-beta-homophenylalanine

Base Information Edit

Chemical Name:Boc-d-beta-homophenylalanine
CAS No.:101555-61-7
Molecular Formula:C15H21NO4
Molecular Weight:279.336
Hs Code.:2924299090
European Community (EC) Number:635-181-0
DSSTox Substance ID:DTXSID50427389
Nikkaji Number:J729.069A
Wikidata:Q72509935
Mol file:101555-61-7.mol

Synonyms:boc-d-beta-homophenylalanine;101555-61-7;(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid;(R)-3-tert-Butoxycarbonylamino-4-phenyl-butyric acid;(R)-3-((tert-butoxycarbonyl)amino)-4-phenylbutanoic acid;(r)-3-(tert-butoxycarbonylamino)-4-phenylbutanoic acid;(3R)-4-[(t-Butoxycarbonyl)amino]-3-phenylbutanoic acid;boc-d-beta-hophe-oh;(R)-3-Boc-amino-4-phenylbutyric acid;MFCD01076270;boc-(r)-3-amino-4-phenylbutyric acid;boc-d-phe-(c*ch2)oh;Boc-D-Phe-(C#CH2)OH;(r)-boc-b2-homophenylalanine;SCHEMBL489489;(R)-3-TERT-BUTOXYCARBONYLAMINO-4-PHENYLBUTYRIC ACID;DTXSID50427389;ACKWQHCPHJQANL-GFCCVEGCSA-N;AKOS016346166;Benzenebutanoic acid, beta-[[(1,1-dimethylethoxy)carbonyl]amino]-, (betaR)-;AC-9074;(r)-3-boc-amino-4-phenyl-butyric acid;Boc-D-beta-homophenylalanine, AldrichCPR;AC-22086;DS-16844;(R)-3-(Boc-amino)-4-phenylbutyric acid;CS-0036367;EN300-391790;(R)-3-t-butoxycarbonylamino-4-phenylbutyric acid;A800404;(R)-3-(tert-Butoxycarbonylamino)-4-phenylbutyric acid;(3R)-3-[(tert-butoxycarbonyl)amino]-4-phenylbutanoic acid;(3R)-3-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoic acid

Suppliers and Price of Boc-d-beta-homophenylalanine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Boc-D-beta-homophenylalanine
100mg
$ 363.00

TRC
Boc-D-β-homophenylalanine
2.5g
$ 475.00

JR MediChem
Benzenebutanoicacid,?-[[(1,1-dimethylethoxy)carbonyl]amino]-,(?R)- 96%
1g
$ 880.00

JR MediChem
Benzenebutanoicacid,?-[[(1,1-dimethylethoxy)carbonyl]amino]-,(?R)- 96%
5g
$ 1980.00

Iris Biotech GmbH
Boc-D-beta-HPhe-OH
5 g
$ 2227.50

Crysdot
Boc-D-beta-Homophenylalanine 95+%
1g
$ 176.00

ChemScene
(R)-3-((tert-Butoxycarbonyl)amino)-4-phenylbutanoicacid
5g
$ 331.00

ChemScene
(R)-3-((tert-Butoxycarbonyl)amino)-4-phenylbutanoicacid
250mg
$ 54.00

ChemPep
Boc-D-β-HoPhe-OH
25g
$ 2730.00

ChemPep
Boc-D-β-HoPhe-OH
5g
$ 910.00

Total 51 raw suppliers

Chemical Property of Boc-d-beta-homophenylalanine Edit

Chemical Property:

Vapor Pressure:1.08E-08mmHg at 25°C
Refractive Index:1.524
Boiling Point:444.837 °C at 760 mmHg
PKA:4.43±0.10(Predicted)
Flash Point:222.829 °C
PSA：75.63000
Density:1.139 g/cm³
LogP:2.98800
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:279.14705815
Heavy Atom Count:20
Complexity:329

Purity/Quality:

98%,99%, ^*data from raw suppliers

Boc-D-beta-homophenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)CC(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](CC1=CC=CC=C1)CC(=O)O
Uses Boc-D-β-homophenylalanine is used in the synthesis of dipeptidyl peptidase IV inhibitors.

Technology Process of Boc-d-beta-homophenylalanine

There total 19 articles about Boc-d-beta-homophenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: (R)-N-Boc-3-benzyl-5-oxoisoxazolidine

: 101555-61-7
(R)-3-t-butoxycarbonylamino-4-phenylbutyric acid

Guidance literature:: With palladium on carbon; hydrogen; In methanol; for 24h; under 68404.6 Torr;
DOI:10.1016/j.cclet.2016.10.005

Reference yield: 90.0%

: 115313-19-4
1-diazo-3(R)-<<(1,1-dimethylethoxy)carbonyl>amino>-4-phenyl-2-butanone

: 101555-61-7
(R)-3-t-butoxycarbonylamino-4-phenylbutyric acid

Guidance literature:: With sodium carbonate; sodium thiosulfate; silver(l) oxide; In 1,4-dioxane; water; for 1h; Heating;
DOI:10.1021/jm00117a025

Reference yield: 86.0%

: 177839-89-3
(R)-tert-butyl 4-hydroxy-1-phenylbutan-2-ylcarbamate

: 101555-61-7
(R)-3-t-butoxycarbonylamino-4-phenylbutyric acid

Guidance literature:: With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile; at 25 ℃; for 1h;
DOI:10.1016/0040-4039(96)00518-7