Technology Process of 2-benzyl-1-bromo-4-chlorobenzene
There total 7 articles about 2-benzyl-1-bromo-4-chlorobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2-bromo-5-chlorophenyl)(phenyl)methanol;
With
trifluoroacetic acid;
In
dichloromethane;
at 0 ℃;
for 0.0333333h;
Inert atmosphere;
Schlenk technique;
With
triethylsilane;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/jacv6b10018
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique
1.2: 2 h / -78 - 20 °C / Inert atmosphere; Schlenk technique
2.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique
2.2: 0 - 20 °C / Inert atmosphere; Schlenk technique
With
n-butyllithium; trifluoroacetic acid;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jacv6b10018
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C
1.2: -78 - 20 °C
2.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique
2.2: 0 - 20 °C / Inert atmosphere; Schlenk technique
With
n-butyllithium; trifluoroacetic acid;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jacs.6b10018
