3,5-Dimethoxybenzyl bromide

Base Information

• Chemical Name: 3,5-Dimethoxybenzyl bromide
• CAS No.: 877-88-3
• Molecular Formula: C9H11BrO2
• Molecular Weight: 231.089
• Hs Code.: 29093090
• European Community (EC) Number: 618-071-7
• DSSTox Substance ID: DTXSID20361564
• Nikkaji Number: J748.861K
• Wikidata: Q72467735
• Mol file: 877-88-3.mol

Synonyms:3,5-Dimethoxybenzyl bromide;877-88-3;1-(bromomethyl)-3,5-dimethoxybenzene;3,5-Dimethoxybenzylbromide;Benzene, 1-(bromomethyl)-3,5-dimethoxy-;alpha-Bromo-3,5-dimethoxytoluene;MFCD01321368;3,5-dimethoxy benzyl bromide;3,5-Dimethoxy benzylbromide;3,5-dimethoxy-benzyl bromide;3, 5-Dimethoxy benzylbromide;SCHEMBL627823;ghl.PD_Mitscher_leg0.1147;DTXSID20361564;3,5-Dimethoxybenzyl bromide, 95%;1-bromomethyl-3,5-dimethoxy-benzene;CK2005;AKOS005259945;CS-W012952;AC-25725;AS-15608;AM20041292;D2657;FT-0601159;A24714;EN300-309108;W-203999;1-(Bromomethyl)-3,5-dimethoxybenzene

Chemical Property of 3,5-Dimethoxybenzyl bromide

Chemical Property:

• Vapor Pressure: 0.00327mmHg at 25°C
• Melting Point: 69-70 °C(lit.)
• Refractive Index: 1.538
• Boiling Point: 292.1 °C at 760 mmHg
• Flash Point: 129.9 °C
• PSA: 18.46000
• Density: 1.384 g/cm³
• LogP: 2.59870
• Storage Temp.: Refrigerator
• Solubility.: soluble in Methanol
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 229.99424
• Heavy Atom Count: 12
• Complexity: 118

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dimethoxybenzyl bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1)CBr)OC
• Uses: 3,5-Dimethoxybenzyl bromide may be used in various organic?synthesis such as?3,4,3′,5′-tetramethoxystilbene; 3,5-dimethoxyphenylacetic acid; 1-(3,5-dimethoxyphenyl)-4-pentene etc., and 3,5-Dimethoxybenzyl bromide may be used as starting material in the multi-step synthesis of resveratroland 3,5-dimethoxyhomophthalic acid. 3,5-Dimethoxybenzyl bromide may be used in the synthesis of:3,4,3′,5′-tetramethoxystilbene3,5-dimethoxyphenylacetic acid1-(3,5-dimethoxyphenyl)-4-penteneIt may be used as starting material in the multi-step synthesis of resveratrol and 3,5-dimethoxyhomophthalic acid. 3,5-DIMETHOXYBENZYL BROMIDE is used in dimethoxybenzene alkyl addition.

Technology Process of 3,5-Dimethoxybenzyl bromide

There total 13 articles about 3,5-Dimethoxybenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-dimethoxybenzyl alcohol (705-76-0) → 3,5-dimethoxybenzyl bromide (877-88-3)

Guidance literature:

With phosphorus tribromide; In benzene; at 20 ℃;

DOI:10.1016/j.jsbmb.2013.02.009

Reference yield: 48.0%

1,3-Dimethoxy-5-(4-methoxy-benzyloxymethyl)-benzene → 3,5-dimethoxybenzyl bromide (877-88-3)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 - 30 ℃; for 1.5h;

DOI:10.1016/S0040-4039(02)01068-7

Reference yield:

3,5-dimethoxybenzaldehdye (7311-34-4) → 3,5-dimethoxybenzyl bromide (877-88-3)

Guidance literature:

With phosphorus tribromide; In dichloromethane; for 1h; Yield given; Ambient temperature;

upstream raw materials:

ethyl 3,5-dimethoxybenzoate

3,5-dimethoxybenzyl alcohol

3,5-dimethoxybenzaldehdye

(3,5-dimethoxyphenyl)methyl methanesulfonate

Downstream raw materials:

2,6-bis<1-(3,5-dimethoxybenzyl)benzimidazol-2-yl>pyridine

1-<3,5-Dimethoxybenzyl>-aethan-1,1,2-tricarbonsaeure-triaethylester

diethyl 3,5-dimethoxybenzylphosphonate

1-(but-3-en-1-yl)-3,5-dimethoxybenzene

Refernces

• 1、 -. "Preparation method of resveratrol". Paragraph 0029; 0033. . Retrieved 2019/12/29.
• 2、 -. "Cancerous Cell Growth Inhibiting Compounds". Paragraph 0179-0180. . Retrieved 2018/01/03.