4-(3,5-DIMETHOXYPHENYL)-1-BUTENE

Base Information

• Chemical Name: 4-(3,5-DIMETHOXYPHENYL)-1-BUTENE
• CAS No.: 111540-02-4
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Hs Code.: 2909309090
• Mol file: 111540-02-4.mol

Synonyms:4-(3,5-DIMETHOXYPHENYL)-1-BUTENE

Chemical Property of 4-(3,5-DIMETHOXYPHENYL)-1-BUTENE

Chemical Property:

• Vapor Pressure: 0.00828mmHg at 25°C
• Boiling Point: 276°C at 760 mmHg
• Flash Point: 102°C
• PSA: 18.46000
• Density: 0.969g/cm³
• LogP: 2.82240

Purity/Quality:

99%min ^*data from raw suppliers

4-(3,5-Dimethoxyphenyl)-1-butene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(3,5-DIMETHOXYPHENYL)-1-BUTENE

There total 5 articles about 4-(3,5-DIMETHOXYPHENYL)-1-BUTENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,5-dimethoxybenzyl bromide (877-88-3) + allylmagnesium bromide (1730-25-2) → 1-(but-3-en-1-yl)-3,5-dimethoxybenzene (111540-02-4)

Guidance literature:

In diethyl ether; at 0 - 20 ℃; for 22h; Inert atmosphere;

DOI:10.1039/c9cc03509e

Reference yield: 69.0%

3,5-dimethoxybenzaldehdye (7311-34-4) + allylsamarium bromide (346713-20-0) → 1-(but-3-en-1-yl)-3,5-dimethoxybenzene (111540-02-4)

Guidance literature:

3,5-dimethoxybenzaldehdye; allylsamarium bromide; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

With phosphonic acid diethyl ester; In tetrahydrofuran; Inert atmosphere;

DOI:10.1039/c3cc45611k

Reference yield:

3,5-dimethoxybenzaldehdye (7311-34-4) → 1-(but-3-en-1-yl)-3,5-dimethoxybenzene (111540-02-4)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorous tribromide / CH₂Cl₂ / 1 h / Ambient temperature

2: 80 percent / diethyl ether / 30 h / Ambient temperature

With phosphorus tribromide; In diethyl ether; dichloromethane;

upstream raw materials:

3,5-dimethoxybenzyl bromide

allylmagnesium bromide

3,5-dimethoxybenzyl alcohol

3,5-dimethoxybenzaldehdye

Downstream raw materials:

abnormal cannabidiol

[pentane-5,5,5-⁽³⁾H₃]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol

C₃₃H₅₅⁽³⁾H₃O₂Si₂

1,5-bis(tert-butyldimethylsilyloxy)-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylbenzene

Refernces

• 1、 Li, Ying,Hu, Yuan-Yuan,Zhang, Song-Lin. "Dual role of allylsamarium bromide as a Grignard reagent and a single electron transfer reagent in the one-pot synthesis of terminal olefins". supporting information. p. 10635 - 10637. Retrieved 2013/11/06.
• 2、 New, Dallas G.,Tesfai, Zerom,Moeller, Kevin D.. "Intramolecular anodic olefin coupling reactions and the use of electron-rich aryl rings". . p. 1578 - 1598. Retrieved 2007/10/03.