4-T-BUTYL-5-METHOXY-O-BENZOQUINONE

Base Information

• Chemical Name: 4-T-BUTYL-5-METHOXY-O-BENZOQUINONE
• CAS No.: 36122-03-9
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Hs Code.: 2914690090
• Mol file: 36122-03-9.mol

Synonyms:o-Benzoquinone,4-tert-butyl-5-methoxy- (7CI);4-Methoxy-5-tert-butyl-1,2-benzoquinone;4-tert-Butyl-5-methoxy-o-benzoquinone;NSC 607536;4-tert-butyl-5-methoxycyclohexa-3,5-diene-1,2-dione;

Chemical Property of 4-T-BUTYL-5-METHOXY-O-BENZOQUINONE

Chemical Property:

• Vapor Pressure: 0.00157mmHg at 25°C
• Refractive Index: 1.495
• Boiling Point: 295 °C at 760 mmHg
• Flash Point: 127.3 °C
• PSA: 43.37000
• Density: 1.08 g/cm³
• LogP: 1.64100
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-tert-Butyl-5-methoxy-o-benzoquinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-T-BUTYL-5-METHOXY-O-BENZOQUINONE

There total 23 articles about 4-T-BUTYL-5-METHOXY-O-BENZOQUINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-tert-butyl-4-methoxyphenol (88-32-4) → 4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9)

Guidance literature:

With potassium dihydrogenphosphate; potassiuim nitrosodisulfonate; In water; acetone;

DOI:10.1002/jps.2600770507

Reference yield: 82.0%

methanol (67-56-1) + 4-(tert-butyl)-5-(4-(tert-butyl)phenoxy)cyclohexa-3,5-diene-1,2-dione (1609537-97-4) → 4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 - 23 ℃; for 4h; Solvent; Reagent/catalyst; Inert atmosphere;

DOI:10.1016/j.tet.2015.04.095

Reference yield: 64.0%

methanol (67-56-1) + 4-tert-Butylcatechol (98-29-3) → 4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9)

Guidance literature:

With sodium periodate; for 1h;

DOI:10.1021/acs.orglett.5b00351

upstream raw materials:

methanol

4-t-butyl-1,2-benzoquinone

4-tert-Butylcatechol

5-tert-butyl-4-methoxy-N-<<2-(2-methoxyethoxy)-5-nitrophenyl>sulfonyl>-o-benzoquinone imine

Downstream raw materials:

4-tert-butyl-5-methoxycatechol

1,2,5-trimethoxy-4-tert-butylbenzene

Refernces

• 1、 Zhang, Ruipu,Qin, Yan,Zhang, Long,Luo, Sanzhong. "Mechanistic Studies on Bioinspired Aerobic C-H Oxidation of Amines with an ortho-Quinone Catalyst". . p. 2542 - 2555. Retrieved 2019/03/08.
• 2、 Huang, Zheng,Kwon, Ohhyeon,Esguerra, Kenneth Virgel N.,Lumb, Jean-Philip. "A divergent and selective synthesis of ortho- and para-quinones from phenols". . p. 5871 - 5885. Retrieved 2015/08/04.