1,2,5-trimethoxy-4-tert-butylbenzene

Base Information

• Chemical Name: 1,2,5-trimethoxy-4-tert-butylbenzene
• CAS No.: 1947-14-4
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.3
• Mol file: 1947-14-4.mol

Synonyms:1,2,5-trimethoxy-4-tert-butylbenzene

Chemical Property of 1,2,5-trimethoxy-4-tert-butylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,5-trimethoxy-4-tert-butylbenzene

There total 4 articles about 1,2,5-trimethoxy-4-tert-butylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-tert-butyl-5-methoxycatechol (91352-66-8) + dimethyl sulfate (77-78-1) → 1,2,5-trimethoxy-4-tert-butylbenzene (1947-14-4)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1002/jps.2600770507

Reference yield:

4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9) → 1,2,5-trimethoxy-4-tert-butylbenzene (1947-14-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / sidium hydrosulfite / aq. ethanol

2: 86 percent / K₂CO₃ / acetone / Heating

With potassium carbonate; sodium hydrogensulfite; In ethanol; acetone;

DOI:10.1002/jps.2600770507

Reference yield:

3-tert-butyl-4-methoxyphenol (88-32-4) → 1,2,5-trimethoxy-4-tert-butylbenzene (1947-14-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / Fremy's salt, KH₂PO₄ / H₂O; acetone

2: 86 percent / sidium hydrosulfite / aq. ethanol

3: 86 percent / K₂CO₃ / acetone / Heating

With potassium dihydrogenphosphate; potassiuim nitrosodisulfonate; potassium carbonate; sodium hydrogensulfite; In ethanol; water; acetone;

DOI:10.1002/jps.2600770507

upstream raw materials:

4-tert-butyl-5-methoxycatechol

dimethyl sulfate

4-tert-butyl-5-methoxy-1,2-benzoquinone

3-tert-butyl-4-methoxyphenol

Refernces