4-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

Base Information

• Chemical Name: 4-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL
• CAS No.: 91352-66-8
• Molecular Formula: C11H16 O3
• Molecular Weight: 196.246
• Mol file: 91352-66-8.mol

Synonyms:Pyrocatechol,4-tert-butyl-5-methoxy- (7CI); NSC 607537

Chemical Property of 4-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

Chemical Property:

• Vapor Pressure: 1.78E-05mmHg at 25°C
• Refractive Index: 1.534
• Boiling Point: 353.2°C at 760 mmHg
• Flash Point: 167.4°C
• PSA: 49.69000
• Density: 1.108g/cm³
• LogP: 2.40390
• Storage Temp.: −20°C

Purity/Quality:

97% ^*data from raw suppliers

4-TERT-BUTYL-5-METHOXYCATECHOL 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

There total 6 articles about 4-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9) → 4-tert-butyl-5-methoxycatechol (91352-66-8)

Guidance literature:

With sodium hydrogensulfite; In ethanol;

DOI:10.1002/jps.2600770507

Reference yield:

1,4-Di-tert-butyl-2,5-dimethoxybenzene radical cation → 4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9) + 1-tert-butyl-2,5-dimethoxy-4-nitro-benzene (99758-88-0) + 2,5-di-tert-butyl-p-benzoquinone (2460-77-7) + 4-tert-butyl-5-methoxycatechol (91352-66-8)

Guidance literature:

With Nitrogen dioxide; In dichloromethane; at 25 ℃; for 0.25h;

DOI:10.3891/acta.chem.scand.51-0031

Reference yield:

tetranitromethane (509-14-8) + 1,4-di-tert-butyl-2,5-dimethoxybenzene (7323-63-9) → 4-tert-butyl-5-methoxy-1,2-benzoquinone (36122-03-9) + 1-tert-butyl-2,5-dimethoxy-4-nitro-benzene (99758-88-0) + 2,5-di-tert-butyl-p-benzoquinone (2460-77-7) + 4-tert-butyl-5-methoxycatechol (91352-66-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 25 ℃; for 1h; Product distribution; Mechanism; Irradiation; reaction temperature varied: -50 to 25 deg C; time: 0.25 to 6 h; solvent also acetonitrile; trifluoroacetic acid concn. 0-1.0 mol dm^-3; nitration also by NO₂ or HNO₃;

DOI:10.3891/acta.chem.scand.51-0031

upstream raw materials:

4-tert-butyl-5-methoxy-1,2-benzoquinone

tetranitromethane

1,4-di-tert-butyl-2,5-dimethoxybenzene

3-tert-butyl-4-methoxyphenol

Downstream raw materials:

4-tert-butyl-5-methoxy-1,2-benzoquinone

1,2,5-trimethoxy-4-tert-butylbenzene

Refernces

• 1、 Svensson, Jan Olof. "Photochemical nitration by tetranitromethane. Part XXXV. A possible addition/elimination pathway in the photochemical reaction of 2,5-di-tert-butyl-1,4-dimethoxybenzene and tetranitromethane". . p. 31 - 36. Retrieved 2007/10/03.