Technology Process of benzyl 5-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylcarbamate
There total 6 articles about benzyl 5-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylcarbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
5-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid;
With
diphenyl phosphoryl azide; triethylamine;
In
benzene;
at 80 ℃;
for 6h;
benzyl alcohol;
In
benzene;
at 80 ℃;
for 30h;
DOI:10.1080/00397911.2010.495043
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: copper(l) iodide / methanol; N,N-dimethyl-formamide / 72 h / Reflux
2.1: sodium hydroxide / methanol; water / 12 h / 20 °C
2.2: pH 2
3.1: ammonia; sodium / tetrahydrofuran / 2.5 h / -70 °C / Inert atmosphere
3.2: ice / pH 3
4.1: diphenyl phosphoryl azide; triethylamine / benzene / 6 h / 80 °C
4.2: 30 h / 80 °C
With
copper(l) iodide; diphenyl phosphoryl azide; ammonia; sodium; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; benzene;
3.1: Birch reduction / 4.1: Curtius rearrangement;
DOI:10.1080/00397911.2010.495043
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: toluene-4-sulfonic acid / 24 h / 64 °C
2.1: copper(l) iodide / methanol; N,N-dimethyl-formamide / 72 h / Reflux
3.1: sodium hydroxide / methanol; water / 12 h / 20 °C
3.2: pH 2
4.1: ammonia; sodium / tetrahydrofuran / 2.5 h / -70 °C / Inert atmosphere
4.2: ice / pH 3
5.1: diphenyl phosphoryl azide; triethylamine / benzene / 6 h / 80 °C
5.2: 30 h / 80 °C
With
copper(l) iodide; diphenyl phosphoryl azide; ammonia; sodium; toluene-4-sulfonic acid; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; benzene;
4.1: Birch reduction / 5.1: Curtius rearrangement;
DOI:10.1080/00397911.2010.495043