1,2-Dibromo-3,4,5,6-tetramethylbenzene

Base Information

• Chemical Name: 1,2-Dibromo-3,4,5,6-tetramethylbenzene
• CAS No.: 36321-73-0
• Molecular Formula: C10H12Br2
• Molecular Weight: 292.013
• Hs Code.: 2903999090
• European Community (EC) Number: 660-322-8
• DSSTox Substance ID: DTXSID40372915
• Nikkaji Number: J1.695.016E
• Wikidata: Q82160892
• Mol file: 36321-73-0.mol

Synonyms:1,2-dibromo-3,4,5,6-tetramethylbenzene;36321-73-0;SCHEMBL3626193;DTXSID40372915;MFCD00154987;AKOS004907393;AS-33086;CS-0153615;FT-0602177;1,2-bis(bromanyl)-3,4,5,6-tetramethyl-benzene;A823205

Chemical Property of 1,2-Dibromo-3,4,5,6-tetramethylbenzene

Chemical Property:

• Vapor Pressure: 0.000475mmHg at 25°C
• Melting Point: 204-205 °C
• Refractive Index: 1.565
• Boiling Point: 324.1 °C at 760 mmHg
• Flash Point: 173.4 °C
• PSA: 0.00000
• Density: 1.562 g/cm³
• LogP: 4.44520
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 291.92853
• Heavy Atom Count: 12
• Complexity: 140

Purity/Quality:

99.3% ^*data from raw suppliers

1,2-Dibromo-3,4,5,6-tetramethylbenzene 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=C(C(=C1C)Br)Br)C)C

Technology Process of 1,2-Dibromo-3,4,5,6-tetramethylbenzene

There total 5 articles about 1,2-Dibromo-3,4,5,6-tetramethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,2,3,4-Tetramethylbenzene (488-23-3) → 1,2-dibromo-3,4,5,6-tetramethylbenzene (36321-73-0)

Guidance literature:

With bromine; iodine; In dichloromethane; for 3h;

DOI:10.1016/j.tetlet.2004.07.116

Reference yield: 85.0%

1,2,3,4-Tetramethylbenzene (488-23-3) → 1-Bromo-2,3,4,5-tetramethylbenzene (40101-36-8) + 1,2-dibromo-3,4,5,6-tetramethylbenzene (36321-73-0)

Guidance literature:

With benzyltrimethylazanium tribroman-2-uide; zinc(II) chloride; In acetic acid; for 2h; Ambient temperature;

DOI:10.1246/bcsj.62.439

Reference yield:

1-Bromo-2,3,4,5-tetramethylbenzene (40101-36-8) → 1,2-dibromo-3,4,5,6-tetramethylbenzene (36321-73-0)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ja01331a061

upstream raw materials:

1-Bromo-2,3,4,5-tetramethylbenzene

1,2,3,4-Tetramethylbenzene

sulfuric acid

Downstream raw materials:

9-Benzhydrylidene-5,6,7,8-tetramethyl-1,4-dihydro-1,4-methano-naphthalene

2-di-tertbutylphosphino-3,4,5,6-tetramethyl-2',4',6'-triisopropyl-1,1'-biphenyl

3,4,5,6-tetramethyl XPHOS

dihydroxyprehnitene

Refernces

• 1、 Vorogushin, Andrei V.,Huang, Xiaohua,Buchwald, Stephen L.. "Use of tunable ligands allows for intermolecular Pd-catalyzed C-O bond formation". . p. 8146 - 8149. Retrieved 2007/10/03.
• 2、 Hellberg, Jonas,Dahlstedt, Emma,Pelcman, Margit E.. "Synthesis of annulated dioxins as electron-rich donors for cation radical salts". . p. 8899 - 8912. Retrieved 2007/10/03.