cycloheptyl formate

Base Information

• Chemical Name: cycloheptyl formate
• CAS No.: 75024-32-7
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• Mol file: 75024-32-7.mol

Synonyms:Cycloheptanol,formate (9CI);Cycloheptyl formate;NSC 80660;

Chemical Property of cycloheptyl formate

Chemical Property:

• Vapor Pressure: 0.534mmHg at 25°C
• Refractive Index: 1.446
• Boiling Point: 190.7 °C at 760 mmHg
• Flash Point: 66.5 °C
• PSA: 26.30000
• Density: 0.97 g/cm³
• LogP: 2.51810

Purity/Quality:

99%, ^*data from raw suppliers

CycloheptylFormate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cycloheptyl formate

There total 4 articles about cycloheptyl formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

formic acid (64-18-6) + Cycloheptene (628-92-2,45509-99-7) → cycloheptyl formate (75024-32-7)

Guidance literature:

With cerium (IV) sulfate; at 50 ℃; for 14h;

Reference yield: 63.0%

cycloheptanecarboxaldehyde (4277-29-6) → cycloheptyl formate (75024-32-7)

Guidance literature:

With water; difluoro[4-(trifluoromethyl)phenyl]-λ³-bromane; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ja104330g

Reference yield: 46.0%

formic acid (64-18-6) + cycloheptanol (502-41-0) → cycloheptyl formate (75024-32-7)

Guidance literature:

With chloro-trimethyl-silane; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1002/1099-1395(200102)14:2<81::AID-POC338>3.0.CO;2-Z

upstream raw materials:

formic acid

cycloheptanol

Cycloheptene

formic acid ethyl ester

Downstream raw materials:

heptanedioic acid

Refernces

• 1、 Ochiai, Masahito,Yoshimura, Akira,Miyamoto, Kazunori,Hayashi, Satoko,Nakanishi, Waro. "Hypervalent λ3-bromane strategy for Baeyer-Villiger oxidation: Selective transformation of primary aliphatic and aromatic aldehydes to formates, which is missing in the classical Baeyer-Villiger oxidation". supporting information; experimental part. p. 9236 - 9239. Retrieved 2010/11/02.
• 2、 Horiuchi, C. Akira,Fukushima, Tomoaki,Furuta, Noriyuki,Chai, Wen,Ji, Shun-Jun,Saito, Yoshikazu,Hashimoto, Chikao,Takahashi, T. Tomoyoshi,Sugiyama, Takashi,Muto, Akinori,Sakata, Yusaku,Nozaki, Sukekatsu. "Esterification of alkene with cerium(IV) sulfate in carboxylic acid". . p. 270 - 272. Retrieved 2007/10/03.