PYRAZINE-2,3-DICARBOXYLIC ACID MONOAMIDE

Base Information

• Chemical Name: PYRAZINE-2,3-DICARBOXYLIC ACID MONOAMIDE
• CAS No.: 67367-37-7
• Molecular Formula: C6H5N3O3
• Molecular Weight: 167.124
• Hs Code.: 2933990090
• Mol file: 67367-37-7.mol

Synonyms:Pyrazinecarboxylic acid, 3-(aminocarbonyl)-(9CI);Pyrazinoic acid, 3-carbamoyl- (6CI);3-Carbamoylpyrazine-2-carboxylic acid;2-pyrazinecarboxylic acid, 3-(aminocarbonyl)-;

Chemical Property of PYRAZINE-2,3-DICARBOXYLIC ACID MONOAMIDE

Chemical Property:

• Melting Point: 156℃ (分解)
• Boiling Point: 464.4 °C at 760 mmHg
• Flash Point: 234.7 °C
• PSA: 106.17000
• Density: 1.56 g/cm³
• LogP: -0.02600

Purity/Quality:

99% ^*data from raw suppliers

3-(Aminocarbonyl)pyrazine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 24/25-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PYRAZINE-2,3-DICARBOXYLIC ACID MONOAMIDE

There total 5 articles about PYRAZINE-2,3-DICARBOXYLIC ACID MONOAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrazine-2,3-dicarboxamide (6164-78-9) → 3-amidecarbonylpyrazine-2-carboxylic acid (67367-37-7)

Guidance literature:

With sodium hydroxide;

Reference yield:

pyrazine-2,3-dicarbonitrile (13481-25-9) → 3-amidecarbonylpyrazine-2-carboxylic acid (67367-37-7)

Guidance literature:

Multi-step reaction with 4 steps

1: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

2: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

3: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

4: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

With K₃Na[Mo(CN)₄O₂]·6H₂O; In ethanol; water;

DOI:10.1016/j.poly.2012.07.006

Reference yield:

3-cyanopyrazine-2-carboxamide (66505-29-1) → 3-amidecarbonylpyrazine-2-carboxylic acid (67367-37-7)

Guidance literature:

Multi-step reaction with 3 steps

1: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

2: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

3: K₃Na[Mo(CN)₄O₂]·6H₂O / ethanol; water / 39.84 °C / pH 8.5

With K₃Na[Mo(CN)₄O₂]·6H₂O; In ethanol; water;

DOI:10.1016/j.poly.2012.07.006

upstream raw materials:

2,3-pyrazinedicarboxylic anhydride

pyrazine-2,3-dicarboxamide

pyrazine-2,3-dicarbonitrile

3-cyanopyrazine-2-carboxamide

Downstream raw materials:

pyrazinamide

2,3-dicarboxypyrazine

3-cyanopyrazine-2-carboxylic acid

N-((3-bromophenyl)(3-cyanopyrazin-2-yl)methylene)-2-methylpropane-2-sulfinamide

Refernces