(SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]]^(2-)-N⁽²¹⁾,N⁽²²⁾,N⁽²³⁾,N⁽²⁴⁾)zinc(II)

Base Information

• Chemical Name: (SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]]^(2-)-N⁽²¹⁾,N⁽²²⁾,N⁽²³⁾,N⁽²⁴⁾)zinc(II)
• CAS No.: 253604-44-3
• Molecular Formula: C₁₀₁H₁₃₈N₁₂O₂₂Zn
• Molecular Weight: 1937.66
• Mol file: 253604-44-3.mol

Synonyms:(SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]]^(2-)-N⁽²¹⁾,N⁽²²⁾,N⁽²³⁾,N⁽²⁴⁾)zinc(II)

Chemical Property of (SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]]^(2-)-N⁽²¹⁾,N⁽²²⁾,N⁽²³⁾,N⁽²⁴⁾)zinc(II)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]]^(2-)-N⁽²¹⁾,N⁽²²⁾,N⁽²³⁾,N⁽²⁴⁾)zinc(II)

There total 1 articles about (SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]]^(2-)-N⁽²¹⁾,N⁽²²⁾,N⁽²³⁾,N⁽²⁴⁾)zinc(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Zn(HCO2CH2CH2CH2O)4C6H3C6H3C20H9N4(C6H2CH3(O(CH2)6C3H3N2)2) (425603-90-3) + 2-[2-(2-methoxyethoxy)ethoxy]ethylamine (74654-07-2,80506-64-5,869718-87-6) → (SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]](2-)-N(21),N(22),N(23),N(24))zinc(II) (253604-44-3)

Guidance literature:

With Et₃N; HATU; In N,N-dimethyl-formamide; Zn-complex was dissolved in DMF, ligand was added, cooled to 0°C,HATU and Et3N were added, stirred at 0°C for 2 h, stirred for 1 d at room temp. under N2 in the dark; solvent was distilled off under vac. at 40°C, residue was taken up in CH2Cl2/MeOH, purified by FC on SiO2 with CH2Cl2/MeOH, concd. in vacuo, dried under vac. overnight, GPC;

DOI:10.1002/1522-2675(200202)85:2<571::AID-HLCA571>3.0.CO;2-Y

Reference yield: 68.0%

hydrogenchloride (7647-01-0,15364-23-5) + (SP-4-2)-([tetrakis[2-[2-(2-methoxyethoxy)ethoxy]ethyl] 4,4',4'',4'''-[10-(3,5-bis[[6-(1H-imidazol-1-yl)hexyl]oxy]-4-methylphenyl)-21H,23H-porphine-1,15-diylbis(benzene-2,1,3-triyldioxy)]tetrakis[butanamido]](2-)-N(21),N(22),N(23),N(24))zinc(II) (253604-44-3) + iron(II) chloride → Fe(OCH2CH2CH2CONH(CH2)6O3CH3)4(C6H3)2C20H9N4(C6H2CH3(O(CH2)6C3H3N2)2)(1+)*Cl(1-)=C101H138FeN12O22Cl (253604-31-8)

Guidance literature:

With 2,6-lutidine; In chloroform; to Zn-complex in CHCl3 at 0°C CF3CO2H was added, stirred at room temp. for 5 min, treated with 2,6-lutidine, washed with H2O, solvent wasdistilled, dried for 2 h, dissolved in THF, 2,6-lutidine was added, ref luxed for 15 min, FeCl2 was added; refluxed for 2 h, cooled to room temp., exposed to air for 30 min, deissolved in CHCl3, HCl in CHCl3, stirred for 5 min, evapd., taken up in THF, 1,8-bis(dimethylamino)naphthalene was added, stirred at room temp. for15 min, concd., GPC, dried for 3 d;

DOI:10.1002/1522-2675(200202)85:2<571::AID-HLCA571>3.0.CO;2-Y

upstream raw materials:

Zn(HCO₂CH₂CH₂CH₂O)4C₆H₃C₆H₃C₂₀H₉N₄(C₆H₂CH₃(O(CH₂)6C₃H₃N₂)2)

2-[2-(2-methoxyethoxy)ethoxy]ethylamine

Downstream raw materials:

Fe(OCH₂CH₂CH₂CONH(CH₂)6O₃CH₃)4(C₆H₃)2C₂₀H₉N₄(C₆H₂CH₃(O(CH₂)6C₃H₃N₂)2)⁽¹⁺⁾*Cl^(1-)=C₁₀₁H₁₃₈FeN₁₂O₂₂Cl

Refernces