l-menthyl 8-quinolinesulfonate

Base Information

• Chemical Name: l-menthyl 8-quinolinesulfonate
• CAS No.: 117800-93-8
• Molecular Formula: C₁₉H₂₅NO₃S
• Molecular Weight: 347.478
• Mol file: 117800-93-8.mol

Synonyms:l-menthyl 8-quinolinesulfonate

Chemical Property of l-menthyl 8-quinolinesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of l-menthyl 8-quinolinesulfonate

There total 2 articles about l-menthyl 8-quinolinesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

quinoline-8-sulfonyl chloride (18704-37-5) + Neomenthol (2216-52-6) → l-menthyl 8-quinolinesulfonate (117800-93-8)

Guidance literature:

In pyridine; at -10 ℃; for 18h;

DOI:10.1021/jo00263a024

Reference yield: 78.0%

quinoline-8-sulfonyl chloride (18704-37-5) + (-)-menthol (2216-51-5) → l-menthyl 8-quinolinesulfonate (117800-93-8)

Guidance literature:

With dmap; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jo900991z

Reference yield: 97.0%

l-menthyl 8-quinolinesulfonate (117800-93-8) → (1S,2R,4R)-2-azido-1-isopropyl-4-methylcyclohexane (898543-45-8,898543-46-9)

Guidance literature:

With trimethylsilylazide; titanium(IV) fluoride; In 1,2-dichloro-ethane; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.200802472

upstream raw materials:

quinoline-8-sulfonyl chloride

Neomenthol

(-)-menthol

Downstream raw materials:

(1S,2R,4R)-2-azido-1-isopropyl-4-methylcyclohexane

p-4⁽⁸⁾-menthene

(1R,2S,5R)-menthyl chloride

neomenthyl chloride

Refernces

• 1、 Corey, E. J.,Posner, Gary H.,Atkinson, Richard F.,Wingard, Astrid K.,Halloran, Daniel J.,et al.. "Formation of Olefins via Pyrolysis of Sulfonate Esters". . p. 389 - 393. Retrieved 2007/10/02.