2-(2-chloroethyl ureido)benzamide

Base Information

• Chemical Name: 2-(2-chloroethyl ureido)benzamide
• CAS No.: 28175-87-3
• Molecular Formula: C₁₀H₁₂ClN₃O₂
• Molecular Weight: 241.677
• Mol file: 28175-87-3.mol

Synonyms:2-(2-chloroethyl ureido)benzamide

Chemical Property of 2-(2-chloroethyl ureido)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-chloroethyl ureido)benzamide

There total 2 articles about 2-(2-chloroethyl ureido)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-chloroethyl isothiocyanate (1943-83-5) + anthranilic acid amide (28144-70-9,88-68-6) → 2-(2-chloroethyl ureido)benzamide (28175-87-3)

Guidance literature:

In acetonitrile; for 2h; Ambient temperature;

Reference yield:

→ 2-(2-chloroethyl ureido)benzamide (28175-87-3)

Guidance literature:

Reference yield: 85.0%

2-(2-chloroethyl ureido)benzamide (28175-87-3) → 2,3-dihydro-5H-oxazolo<2,3-b>quinazolin-5-one (52727-44-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; for 24h; Heating;

upstream raw materials:

2-chloroethyl isothiocyanate

anthranilic acid amide

Downstream raw materials:

2,3-dihydro-5H-oxazolo<2,3-b>quinazolin-5-one

3-(2-chloroethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline

Refernces