CID 4041419

Base Information

• Chemical Name: CID 4041419
• CAS No.: 14783-10-9
• Molecular Formula: C12H8 Cl2 N2 Pd
• Molecular Weight: 357.535
• Mol file: 14783-10-9.mol

Synonyms:CS-W011831

Chemical Property of CID 4041419

Chemical Property:

• Vapor Pressure: 3.38E-05mmHg at 25°C
• Boiling Point: 365.1°C at 760 mmHg
• Flash Point: 164.8°C
• PSA: 25.78000
• LogP: -3.20900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 355.90993
• Heavy Atom Count: 17
• Complexity: 209

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dichloro(1,10-phenanthroline)palladium(II) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.Cl[Pd]Cl
• Uses: Catalyst for:Carbonylation of alkyl nitritesArylation reactionsMultiple acetylene insertions under Sonogashira reaction protocolCross-coupling reactions of pyridine carboxylic acid chlorides with alkylzinc reagentsHydrophosphinylation of alkenes and alkynesHeck reactionRegioselective and stereoselective aminohalogenation reactionsReaction of chloroenynes and chlorodienes with Grignard reagents for the synthesis of stereodefined enynes and dienesAffects the aggregation of human prion protein PrP106-126

Technology Process of CID 4041419

There total 21 articles about CID 4041419 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,10-phenanthroline hydrate (5144-89-8) + palladium dichloride → [palladium(II)dichloride(1,10-phenanthroline)] (14783-10-9)

Guidance literature:

With hydrogenchloride; In ethanol; water; addn. of concd. HCl to an aq. PdCl2 soln., filtration of the soln. and addn. of a soln of 1,10-phenanthroloine*H2O in ethanol to the filtered soln.; stirring for 2 h, filtering the ppt., washing with ethanol and drying in vacuo, elem. anal.;

DOI:10.1016/0304-5102(86)87038-9

Reference yield: 95.0%

1,10-Phenanthroline (66-71-7) + potassium tetrachloropalladate(II) (10025-98-6) → [palladium(II)dichloride(1,10-phenanthroline)] (14783-10-9)

Guidance literature:

at 35 - 40 ℃;

DOI:10.1080/15533174.2013.862652

Reference yield: 94.0%

trans-(S,S)-[PdCl2(NH2CH(CO2Me)CH2C8H5N-I-2)2] + 1,10-phenanthroline hydrate (5144-89-8) → [palladium(II)dichloride(1,10-phenanthroline)] (14783-10-9)

Guidance literature:

In dichloromethane; byproducts: (S)-2-I-C8H5N-CH2CH(CO2CH3)NH2; ligand added to a soln. of Pd complex, stirred for 4 h; filtered;

DOI:10.1021/om0506522

upstream raw materials:

1,10-phenanthroline hydrate

palladium

1,10-Phenanthroline

potassium tetrachloropalladate(II)

Downstream raw materials:

PdCl(CON(CH₂)5)(1,10-phenanthroline)

piperidine hydrochloride

Pd(CON(CH₂)5)2(1,10-phenanthroline)

Refernces

• 1、 Cipriani, Micaella,Docampo, Roberto,Etcheverry, Susana,Gambino, Dinorah,Gancheff, Jorge S.,Kemmerling, Ulrike,Li, Zhu-Hong,Olea Azar, Claudio,León, Ignacio,Otero, Lucía,Rostán, Santiago. "Multi-target heteroleptic palladium bisphosphonate complexes". . . Retrieved 2020/04/03.
• 2、 G?k, Lütfiye,Günnaz, Salih,?ahin, Zarife Sibel,Pelit, Levent,Türkmen, Hayati. "The imidazo{[4,5-f][1,10]-phenanthrolin}l-2-ylidene and its palladium complexes: Synthesis, characterization, and application in C-C cross-coupling reactions". . p. 96 - 104. Retrieved 2016/11/21.