Pyrimidine, 2-(methylsulfinyl)- (8CI,9CI)

Base Information

• Chemical Name: Pyrimidine, 2-(methylsulfinyl)- (8CI,9CI)
• CAS No.: 14080-19-4
• Molecular Formula: C5H6 N2 O S
• Molecular Weight: 142.17894
• Hs Code.: 29335990
• Mol file: 14080-19-4.mol

Synonyms:Pyrimidine, 2-(methylsulfinyl)- (8CI,9CI)

Chemical Property of Pyrimidine, 2-(methylsulfinyl)- (8CI,9CI)

Chemical Property:

• PSA: 62.06000
• LogP: 1.07970
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

2-(Methylsulfinyl)pyrimidine 97% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrimidine, 2-(methylsulfinyl)- (8CI,9CI)

There total 1 articles about Pyrimidine, 2-(methylsulfinyl)- (8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(methylsulfanyl)pyrimidine (823-09-6) → 2-(methylsulfinyl)pyrimidine (14080-19-4,944111-39-1)

Guidance literature:

With dihydrogen peroxide; 1-ethyl-3-methylimidazolium tetrafluoroborate; Ti-Ge-MCM-41; In 1,4-dioxane; at 40 ℃; for 0.5h;

DOI:10.1002/chem.200400105

Reference yield: 70.0%

p-nitrobenzenesulfonamide (6325-93-5) + 2-(methylsulfinyl)pyrimidine (14080-19-4,944111-39-1) → N-(4-nitrobenzenesulfonyl) methyl (2-pyrimidinyl) sulfoximine

Guidance literature:

With iodosylbenzene; iron(III) acetylacetonate; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1002/chem.200700352

Reference yield: 39.0%

2-(methylsulfinyl)pyrimidine (14080-19-4,944111-39-1) + benzylmagnesium chloride (6921-34-2) → benzyl-pyrimidine (90210-57-4)

Guidance literature:

In tetrahydrofuran; Ambient temperature;

upstream raw materials:

2-(methylsulfanyl)pyrimidine

Downstream raw materials:

benzyl-pyrimidine

Refernces

• 1、 Cimpeanu, Valentin,Parvulescu, Vasile I.,Amoros, Pedro,Beltran, Daniel,Thompson, Jillian M.,Hardacre, Christopher. "Heterogeneous oxidation of pyrimidine and alkyl thioethers in ionic liquids over mesoporous Ti or Ti/Ge catalysts". . p. 4640 - 4646. Retrieved 2007/10/03.