1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine

Base Information

• Chemical Name: 1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine
• CAS No.: 141766-05-4
• Molecular Formula: C₂₄H₃₈N₄O₄S₂
• Molecular Weight: 510.722
• Mol file: 141766-05-4.mol

Synonyms:1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine

Chemical Property of 1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine

There total 2 articles about 1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-Methyl-N-(4-toluenesulphonyl)iodoethylamine (3409-85-6) + N,N`-dimethylethylenediamine (110-70-3) → 1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine (141766-05-4)

Guidance literature:

With potassium carbonate; In acetonitrile; for 10h; Heating;

DOI:10.1016/0040-4039(92)88177-7

Reference yield:

toluene-4-sulfonic acid 2-[methyl-(toluene-4-sulfonyl)-amino]-ethyl ester (3559-06-6) → 1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine (141766-05-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / NaI / acetone / Heating

2: 99 percent / K₂CO₃ / acetonitrile / 10 h / Heating

With potassium carbonate; sodium iodide; In acetone; acetonitrile;

DOI:10.1016/0040-4039(92)88177-7

Reference yield: 96.0%

1,10-Ditosyl-1,4,7,10-tetramethyltriethylenetetramine (141766-05-4) → 1,4,7,10-tetramethyl-1,4,7,10-tetraazadecane (105-78-2)

Guidance literature:

With lithium aluminium tetrahydride; In 1,2-dimethoxyethane; for 20h; Heating;

DOI:10.1016/0040-4039(92)88177-7

upstream raw materials:

N-Methyl-N-(4-toluenesulphonyl)iodoethylamine

N,N`-dimethylethylenediamine

toluene-4-sulfonic acid 2-[methyl-(toluene-4-sulfonyl)-amino]-ethyl ester

Downstream raw materials:

1,4,7,10-tetramethyl-1,4,7,10-tetraazadecane

1,16-Ditosyl-1,4,7,10,13,16-hexamethylpentaethylenehexamine

Refernces